Molecular and elemental contrast microscopy for biochemical fingerprinting of the cellular action mechanisms underlying tDCS in appetite control

Transcranial direct current brain stimulation (tDCS) has recently emerged as a novel noninvasive alternative for treating food addiction via modulating cortical excitability. Unfortunately, the action mechanism of tDCS has not been precisely defined as complex neurochemical pathways are involved in its molecular effects, and of particular interest are those related to its relation with energy metabolism in the brain. Recently, it was proposed that tDCS may be associated with increased permeability for ions as well as small and large molecules, thus suggesting the interplay between elemental and molecular changes.

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: A. Surowka, A. Ziomber, M. Czyzycki, A. Gianoncelli, D. Bedolla, G. Birarda, K. Kasper, M. Szczerbowska-Boruchowska, L. Vaccari Source Type: research