Towards a mechanistic understanding of brain stimulation

Repetitive TMS (rTMS) represent the front-line of innovative approaches to correct dysfunctional brain networks. rTMS is FDA-approved for patients with depression, OCD and clinical trials for PTSD and substance use are underway. Despite this increasing use, knowledge of how repetitive stimulation induces brain plasticity in humans is critically lacking and will be necessary to develop next-generation personalized brain stimulation treatments. Here, we investigate the neural mechanisms underlying rTMS using direct brain recordings with high spatiotemporal resolution.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - Category: Neurology Authors: Source Type: research