Dimensional biotype-based TMS personalization

Evidence for the efficacy of TMS in disorders other than major depression have demonstrated variable results. This underscores the need to improve the reliability and effectiveness of TMS interventions which may be achieved through treatment personalization. We focus on two considerations in personalizing treatment according to dimensional biotypes: 1) behavioural and clinical symptoms, and 2) changes in excitability and connectivity. Dimensional biotypes reveal characteristics that are common across disorders such as problems with attention and concentration in major depression, ADHD, and narcolepsy or avolition in major depression, schizophrenia, and bipolar disorder.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - Category: Neurology Authors: Source Type: research