Mosquito larvicidal limonoids from the fruits of Chisocheton erythrocarpus Hiern

Publication date: April 2019Source: Phytochemistry Letters, Volume 30Author(s): Soon-Lim Chong, Arshia Hematpoor, Hazrina Hazni, Mohd Sofian-Azirun, Marc Litaudon, Unang Supratman, Michio Murata, Khalijah AwangAbstractA phytochemical investigation on the fruits of Chisocheton erythrocarpus Hiern (Meliaceae) afforded four new limonoids, erythrocarpines F–H (1–3) and 14-deoxy-Δ1415-xyloccensin K (4), along with seven known compounds (5-11). Erythrocarpines 1–3 are phragmalin-type limonoids with an 1,29-oxymethylene bridge, while 4 is a mexicanolide-type limonoid possessing a rare 3β,8β-ether linkage. Mosquito larvicidal activity of the limonoids revealed that 4 and 5 were toxic to larvae of Aedes aegypti, Aedes albopictus and Culex Quinquefasciatus.Graphical abstract

Source: Phytochemistry Letters - January 21, 2019 Category: Chemistry Source Type: research