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Genetic Big Data: What It Means

Researchers finished the first draft of the human genome in the year 2000. Although the decreasing cost of the technology has far outpaced Moore’s Law since then, we have yet to fully leverage all that new information to make it really useful. In a wide ranging talk on his work, from transcribing the first complete human genome to building synthetic life forms, genomic pioneer Craig Venter confessed he was disappointed that genomics has taken as long as it has to scale up. “We just got to the starting line,” Venter said, speaking at Singularity University’s Exponential Medicine conference. “Hopefully it won’t take as long to get through it as it took to get started.” What’s changed? Earlier this year, genomic sequencing company, Illumina, announced a new sequencing system that can produce 18,000 high quality human genomes per year at $1,000 per genome -- a mark dreamed of for over a decade. Venter’s new venture, Human Longevity, Inc., purchased two of Illumina’s new sequencers with the aim of ramping up to some 40,000 genomes a year. When asked what’s coming in the next five years, Venter quipped that predicting the future is hard unless you’re an investor, but he thinks a big acceleration is in the cards. “[We’re going to go] from zero to a thousand miles an hour very quickly.” Whereas we’ve sequenced around 225,000 genomes worldwide to date, Venter estimates we’ll h...
Source: Science - The Huffington Post - Category: Science Source Type: news

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ConclusionBreast cancer patients with mental illness should be closely managed by a cross-functional care team, including a psychiatrist, a primary care physician, and an oncologist, to ensure adequate care is received within an appropriate timeframe.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research
Tracy Thompson begins her thoughtful book The Ghost in the House with two brilliant sentences: “Motherhood and depression are two countries with a long common border. The terrain is chilly and inhospitable, and when mothers speak of it at all, it is usually in guarded terms, or in euphemisms.” If depression happened in a vacuum, it would be so much easier. But it doesn’t. It happens in the context of a family, raising kids, being responsible for other human beings even as you can’t take care of yourself. My Worst Fear for My Children “Even when it is relatively mild, depression may cause ...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Bipolar Books Brain and Behavior Depression Parenting Personal Source Type: blogs
"For every complex problem there is an answer that is clear, simple, and wrong." H. L. Mencken The nature/nurture debate on the causes of mental disorder generates no end of silly controversy by proponents on both sides. The biological reductionists act like the secret of psychiatric disorders is written in the genetic code. They are "mindless"- dismissing the crucial role of environment in how our brain develops and of psychology and social context in how it functions. The environmental reductionists go to the opposite "brainless" extreme- argueing that a psychiatric disorder is a direct r...
Source: Science - The Huffington Post - Category: Science Source Type: news
The approval of first-of-a-kind drugs rose last year to forty-one, resulting in the highest level of newly approved U.S. drugs in nineteen years. The total number of new drugs approved last year was even higher at sixty-nine. The rising figures reflect an industry-wide desire to research and develop drugs for rare and hard-to-treat diseases. The newly approved drugs serve to advance medical care and the health of patients suffering from many ailments, including various forms of cancer, heart failure, and cystic fibrosis. Additionally, more than 40% of the new therapies were approved for treatment of rare or "orphan&...
Source: Policy and Medicine - Category: American Health Authors: Source Type: blogs
This study aimed to determine whether depression or bipolar recorded in routine hospital admission data independently predicts survival in English breast cancer patients and whether onset in relation to cancer diagnosis is significant. MethodsData on 77 173 women diagnosed with breast cancer (ICD‐10 C50) in South East England, 2000–2009, were included. Of these, 131 women had a diagnosis of bipolar affective disorder (ICD‐10 F31) and 955 of depression (either depressive episodes (ICD‐10 F32) or depressive disorder (ICD‐10 F33)) recorded in Hospital Episode Statistics between 3 years before and a yea...
Source: Psycho-Oncology - Category: Cancer & Oncology Authors: Tags: Paper Source Type: research
Our daughter celebrates her birthday each June. I can't help but measure her birthdays with an equal sense of apprehension and elation. She's a teenager now, and still no sign of the brooding, the polarity, the darkness that descended on my husband like Portland's thick gray clouds in January, refusing to budge. Yes, she has his intellect but she also has my relatively sunny nature. She is physically stunning with long, muscular legs and a waist that defies her voracious appetite. She has David's European cheekbones. The color of her skin is his. Her ears have the same shape. There are times I find myself staring at one of...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
The stress hormone cortisol exhibits a diurnal rhythm throughout the day, as well as within person variability. Recent statistical approaches allow for the estimation of intraindividual cortisol variability (“ICV”) and a greater ICV has been observed in some mood disorders (major depression, remitted bipolar disorder); however, ICV has not been examined following stress management. In this secondary analyses of an efficacious randomized clinical trial, we examine how ICV may change after cognitive behavioral stress management (CBSM) among healthy stressed women at risk for breast cancer.
Source: Journal of Psychosomatic Research - Category: Psychiatry & Psychology Authors: Source Type: research
This article '8 Weird Things That Happen When You Send A Text' originally ran on Prevention.com. More from Prevention.com: 7 Things To Never Do Before Or After Sex 9 Proven Ways To Lose Stubborn Belly Fat This Haircut Will Make You Look 10 Years Younger Shrink A Size In Just 14 Days 6 Simple Moves To Ease Sciatica Also on HuffPost: -- This feed and its contents are the property of The Huffington Post, and use is subject to our terms. It may be used for personal consumption, but may not be distributed on a website.
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
Too many doctors refuse to think outside the narrow confines of the mainstream medical establishment – especially when it comes to chronic back pain. Back pain is one of the most common reasons Americans go to the doctor, which explains why it’s also one of America’s biggest businesses. But I never cease to be astounded when patients come to my wellness clinic with back pain and tell me they’ve already had a barrage of dangerous Big Pharma prescriptions pushed at them. These drugs include highly addictive opiates like Vicodin, Percocet and OxyContin. Meanwhile, big bucks are also made when doctors p...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Anti-Aging Source Type: news
Imagine if people reacted to a friend or neighbor’s diagnosis of bipolar disorder or depression no differently than if they just learned that person has breast cancer or heart disease. “Whether an illness affects your heart, your leg or your brain, it’s still an illness. It shouldn’t be treated differently,” said First Lady Michelle Obama...continue reading
Source: Counseling Today - Category: Psychiatry & Psychology Authors: Tags: Counseling Today Online Exclusives Counselors Audience Mental Health stigma Source Type: research
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