Estimation of impact of RPE65-mediated inherited retinal disease on quality of life and the potential benefits of gene therapy.

CONCLUSION: This is the first study to report HRQL weights (or utilities) for health states describing different levels of vision loss in patients with IRD, specifically those with RPE65-mediated disease. The parallel decline in scores from the EQ-5D and HUI3 corroborates the substantial impact of progressive vision loss on HRQL.
PMID: 30658988 [PubMed - as supplied by publisher]

Source: The British Journal of Ophthalmology - January 18, 2019 Category: Opthalmology Authors: Lloyd A, Piglowska N, Ciulla T, Pitluck S, Johnson S, Buessing M, O'Connell T Tags: Br J Ophthalmol Source Type: research