Neuropeptide VGF-Derived Peptide LQEQ-19 has Neuroprotective Effects in an In Vitro Model of Amyotrophic Lateral Sclerosis.

In conclusion, these results suggest that VGF C-terminal peptides exert their neuroprotective effects via activation of MAPKs such as Akt and ERK1/2. Furthermore, these findings indicate that VGF-derived peptides have potential application in ALS therapy. PMID: 30656593 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30656593?dopt=Abstract

Source: Neurochemical Research - January 17, 2019 Category: Neuroscience Authors: Noda Y, Motoyama S, Nakamura S, Shimazawa M, Hara H Tags: Neurochem Res Source Type: research