Long non-coding RNA polymorphisms influence susceptibility to endemic pemphigus foliaceus.

CONCLUSION: We showed, for the first time, that variation in lncRNA genes may influence pemphigus pathogenesis. Our findings highlight the importance of lncRNA variation in autoimmune and possibly other complex diseases and suggest polymorphisms for functional validation. This article is protected by copyright. All rights reserved.
PMID: 30653253 [PubMed - as supplied by publisher]

Source: The British Journal of Dermatology - January 17, 2019 Category: Dermatology Authors: Lobo-Alves SC, Augusto DG, Magalhães WCS, Tarazona-Santos E, Lima-Costa MF, Barreto ML, Horta BL, de Almeida RC, Petzl-Erler ML Tags: Br J Dermatol Source Type: research