Dual RAAS Blockade No Better Than ACE Inhibitor to Slow PKDDual RAAS Blockade No Better Than ACE Inhibitor to Slow PKD

In early or moderate autosomal dominant polycystic kidney disease, dual RAAS blockade did not slow the long-term decline in kidney function when compared with an ACE inhibitor alone. Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Nephrology News Source Type: news

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Conclusions24 weeks of aldosterone antagonism reduced systolic blood pressure without changing vascular function in patients with early-stage ADPKD.FundingNIDDK, NIH National Center for Advancing Translational Sciences, and the Zell Family Foundation.Trial RegistrationRegistered at ClinicalTrials.gov with study number NCT01853553.
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
We present results from the use of 3% STS foam sclerotherapy.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific Session 43: Follow Your Gut Source Type: research
Radiology, Ahead of Print.
Source: Radiology - Category: Radiology Authors: Source Type: research
Radiology, Ahead of Print.
Source: Radiology - Category: Radiology Authors: Source Type: research
ConclusionDTI of the kidneys shows significantly lower FA values and mean track length in children and young adults with ARPKD compared to normal subjects. DTI of the kidney offers a novel approach for characterizing renal disease based on changes in diffusion anisotropy and kidney structure.
Source: Abdominal Imaging - Category: Radiology Source Type: research
Autosomal dominant polycystic kidney disease (ADPKD) affects all races. Whether the progression of ADPKD varies by race remains unclear.
Source: BMC Nephrology - Category: Urology & Nephrology Authors: Tags: Research article Source Type: research
Elizabeth Waldrop, Mohammed A. I. Al-Obaide, Tetyana L. Vasylyeva
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
CONCLUSION: People with diverticulosis are more likely to have colonic extracellular matrix (ECM)/connective tissue alterations in anatomical areas other than the bowel, suggesting linked ECM/connective tissue pathology. Although biases may exist, the results indicate large-scale integrated studies are needed to investigate underlying genetic pathophysiology of colonic diverticula, together with fundamental biological studies to investigate cellular phenotypes and ECM changes. PMID: 30719942 [PubMed - as supplied by publisher]
Source: Connective Tissue Research - Category: Research Tags: Connect Tissue Res Source Type: research
Authors: Dong K, Miao H, Jia X, Wu J, Wu H, Sun J, Ji W, Su H, Xu L, Zhang X, Zhu S, Ji G, Guan R, Wang H, Bai J, Yu J, Sun W, Zhou X, Fu S Abstract Polycystic kidney disease (PKD) is a life‑threatening inherited disease with a morbidity of 1:500‑1,000 worldwide. Numerous progressively enlarging cysts are observed in the bilateral kidneys of patients with PKD, inducing structural damage and loss of kidney function. The present study analyzed one family with PKD. Whole exome sequencing of the proband was performed to detect the pathogenic gene present in the family. Candidate gene segments for lineal consanguini...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Learn more about polycystic kidney disease. Other health tip infographics: mayohealthhighlights.startribune.com?
Source: News from Mayo Clinic - Category: Databases & Libraries Source Type: news
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