Long-term survival estimates in older patients with pathological stage I gastric cancer undergoing gastrectomy: Duocentric analysis of simplified scoring system

Publication date: Available online 17 January 2019Source: Journal of Geriatric OncologyAuthor(s): Katsunobu Sakurai, Naoshi Kubo, Yutaka Tamamori, Tatsuro Tamura, Takahiro Toyokawa, Hiroaki Tanaka, Kazuya Muguruma, Masakazu Yashiro, Kiyoshi Maeda, Yukio Nishiguchi, Kosei Hirakawa, Masaichi OhiraAbstractBackgroundOur aim was to determine factors predictive of long-term post-gastrectomy outcomes in older adults with pathological stage I gastric cancer (GC).MethodsA total of 175 patients with resected pathological stage I GC at two institutions were reviewed, each ≥75 years old at the time of gastrectomy and full participants in a 5-year follow-up program. The procedures were undertaken between January 2006 and December 2011. Patients were divided into two groups: survivors and non-survivors at postoperative Year 5. Univariate and multivariate analyses were applied to identify independent predictors of 5-years survival, including preoperative, surgical, and histopathologic variables.ResultsMultivariate analysis of overall survival (OS) at 5 years indicated that prognostic nutritional index (PNI)
Source: Journal of Geriatric Oncology - Category: Cancer & Oncology Source Type: research

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Background: The aim of this study was to determine whether or not the short- and long-term outcomes were affected by the age-adjusted Charlson comorbidity index (ACCI) in patients who underwent curative resection for gastric cancer.Methods: The patients were retrospectively selected from among the medical records of consecutive patients who underwent curative gastrectomy with nodal dissection for gastric cancer at Yokohama City University and Kanagawa Cancer Center from January 2000 to August 2015.Results: A total of 2254 patients were eligible for inclusion in the present study. One thousand six hundred fifty-six patients had an ACCI of
Source: Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Research Paper Source Type: research
Publication date: Available online 9 December 2019Source: European Journal of Integrative MedicineAuthor(s): Xiao-Qing Wang, Pei-Bei Duan, Man Zheng, Qian Xu, Li-Hua Yang, A-Qin WangAbstractIntroductionAuricular acupuncture has been used for pain management. A more recent technique which buries an intradermal needle into the skin may provides long lasting stimulation and enhance analgesia. The purpose of this study was to evaluate the efficacy and feasibility of perioperative auricular acupuncture technique via intradermal needling buried on postoperative movement-evoked pain reduction of patients with advanced gastric can...
Source: European Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research
AbstractBackgroundLaparoscopic gastrectomy (LG) is an established minimally invasive procedure for gastric cancer. However, it is controversial whether LG is useful for patients with poor physical status classified into higher classes of the American Society of Anesthesiologists physical status (ASA-PS) classification. The aim of this study was to determine the feasibility of LG in patients with ASA-PS class  ≥ 3.MethodsWe extracted data for a total of 28,160 patients with an ASA-PS class  ≥ 3 who underwent distal or total gastrectomy for gastric cancer between January 2013 and December 20...
Source: Gastric Cancer - Category: Gastroenterology Source Type: research
Conclusions: Advanced stage, application of neoadjuvant therapy, low BMI level, and poor postoperative appetite may deteriorate the postoperative QoL of the patients with gastric cancer.
Source: Nigerian Journal of Clinical Practice - Category: Rural Health Authors: Source Type: research
A 64-YEAR-OLD, 70-kg, 170-cm man presented to the emergency department of the authors ’ institution with acute onset of nausea, vomiting, and diffuse abdominal pain. The patient denied fever, chills, weight loss, heartburn, dysphagia, hematemesis, melena, hematochezia, constipation, abdominal distention, and urinary symptoms. He stated that he had been well until the morning of adm ission. The patient's medical history was notable for gastric cancer that was initially treated with neoadjuvant chemotherapy (consisting of folinic acid, 5-fluorouracil, and oxaliplatin) and radiation therapy (total of 45 Gy in divided do...
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Diagnostic Dilemma Source Type: research
AbstractBackgroundLaparoscopic gastrectomy is becoming more commonly performed, but acquisition of its technique remains challenging. We investigated whether laparoscopy-assisted distal gastrectomy (LDG) performed by trainees (TR) supervised by a technically qualified experienced surgeon (QS) is feasible and safe.MethodsThe short-term outcomes of LDG were assessed in patients with gastric cancer between 2008 and 2018. We compared patients who underwent LDG performed by qualified experienced surgeons (QS group) with patients who underwent LDG performed by the trainees (TR group).ResultsThe operation time was longer in the T...
Source: Surgical Endoscopy - Category: Surgery Source Type: research
Conclusions: In addition to being technically feasible for treatment of AGC in terms of morbidity, LG with D2 LND for locally advanced gastric cancer showed acceptable 3-year DFS outcomes. Trial Registration: ClinicalTrials.gov Identifier: NCT01441336. PMID: 30944763 [PubMed]
Source: Journal of Gastric Cancer - Category: Gastroenterology Tags: J Gastric Cancer Source Type: research
Conclusions: If ultrasound-guided bilateral RSB with 40 mL of 0.35% ropivacaine is performed precisely in patients undergoing open gastrectomy, the requirement for remifentanil during surgery can be reduced. In addition, it significantly reduces the use of PCA bolus dose for acute postoperative pain within 2 hours after surgery.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Trial/Experimental Study Source Type: research
ConclusionsThis study represents the first prospective feasibility evaluation of sentinel lymph node sampling for early gastric cancer in North America with promising preliminary results. The dual tracer method was superior to single agent blue dye in identifying sentinel nodal basins. Considerable further study is necessary to verify the safety and utility of SLN mapping in North American patients with early gastric adenocarcinoma.
Source: Journal of Gastrointestinal Surgery - Category: Surgery Source Type: research
This study aimed to compare outcomes following laparoscopic versus open gastrectomy for advanced gastric cancer at a regional institution in Hong Kong. METHODS: Fifty-four patients who underwent laparoscopic gastrectomy from January 2009 to March 2017 were compared with 167 patients who underwent open gastrectomy during the same period. All had clinical T2 to T4 lesions and underwent curative-intent surgery. The two groups were matched for age, sex, American Society of Anaesthesiologists class, tumour location, morphology, and clinical stage. The endpoints were perioperative and long-term outcomes including survival a...
Source: Hong Kong Med J - Category: General Medicine Authors: Tags: Hong Kong Med J Source Type: research
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