5-aminolevulinic acid photodynamic therapy for the treatment of high-grade gliomas
ConclusionPDT remains a promising therapeutic approach that requires further study in HGGs. Use of 5-ALA PDT permits selective tumor targeting due to the intracellular metabolism of 5-ALA. The immunomodulatory effects of PDT further strengthen its use for treatment of HGGs and requires a better understanding. The combination of PDT with adjuvant therapies for HGGs will need to be studied in randomized, controlled studies.
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research
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