Alteration in gut microbiota associated with hepatitis B and non-hepatitis virus related hepatocellular carcinoma

ConclusionsOur study indicated that B-HCC and NBNC-HCC patients showed differential abundance of bacteria involved in different functions or biological pathways. We suggested the modification of specific gut microbiota may provide the therapeutic benefit for B-HCC and NBNC-HCC.
Source: Gut Pathogens - Category: Microbiology Source Type: research

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Publication date: Available online 22 October 2019Source: Biosensors and BioelectronicsAuthor(s): Mohammed Sedki, Xingyu Chen, Chuan Chen, Xin Ge, Ashok MulchandaniAbstractA highly sensitive and selective non-lytic M13 phage-based electrochemical impedance spectroscopy (EIS) cytosensor for early detection of coliforms is introduced for the first time. AuNPs were electrochemically deposited on the surface of glassy carbon electrode, and the M13 phage particles were immobilized on them using 3-mercaptopropanoic acid linker and zero-length crosslinking chemistry (EDC/NHS). Next, the sensor surface was blocked to avoid non-spe...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
Publication date: Available online 23 October 2019Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): V. Arroyo-Jousse, A. Jaramillo, E. Castaño-Moreno, M. Lépez, K. Carrasco-Negüe, P. CasanelloAbstractMaternal pregestational obesity is a well-known risk factor for offspring obesity, metabolic syndrome, cardiovascular disease and type 2 diabetes. The mechanisms by which maternal obesity can induce alterations in fetal and later neonatal metabolism are not fully elucidated due to its complexity and multifactorial causes. Two adipokines, leptin and adiponectin, are involved i...
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - Category: Molecular Biology Source Type: research
The objective of this study was to determine the carrying of STEC in Paraguayan bovines and to analyze the virulence profile and serotypes of these isolates. A total of 197 samples of bovine fecal samples and an average of 5 to 50 colonies from stx1/stx2 positive samples were studied. The stx1, stx2, saa, ehxA and eae genes were amplified by PCR. 84.8% of the cattle were carriers of STEC. The predominant virulence profiles were stx2 and stx2/saa/ehxA. The serotyping was performed by agglutination reactions for 60 selected isolates, resulting in isolation of serogroup O103, which could produce infections in humans. This wor...
Source: Revista Argentina de Microbiologia - Category: Microbiology Tags: Rev Argent Microbiol Source Type: research
Publication date: Available online 23 October 2019Source: The Journal of Steroid Biochemistry and Molecular BiologyAuthor(s): Margarida Lorigo, Melissa Mariana, Manuel C. Lemos, Elisa CairraoAbstractTestosterone (T) is the predominant endogenous androgen in the bloodstream. At the vascular level, T presents genomic and non-genomic effects, and both effects may overlap. The genomic actions assume that androgens can freely cross the plasma membrane of target cells and bind to nuclear androgen receptors, inducing gene transcription and protein synthesis. The non-genomic effects have a more rapid onset and may be related to th...
Source: The Journal of Steroid Biochemistry and Molecular Biology - Category: Biochemistry Source Type: research
Publication date: Available online 22 October 2019Source: Pharmacology Biochemistry and BehaviorAuthor(s): Steven Wesley Beckwith, Cristine Lynn CzachowskiAbstractIncreased subjective discounting of delayed rewards is associated with substance abuse, and individuals tend to discount their drug of choice at a greater rate compared to monetary rewards. While there is evidence indicating that increased delay discounting (DD) is a risk factor for substance abuse, some results suggest that exposure to drugs of abuse also increases DD, but effects are mixed. The current study examined whether ethanol pre-exposure increases DD an...
Source: Pharmacology Biochemistry and Behavior - Category: Biochemistry Source Type: research
Publication date: Available online 22 October 2019Source: Journal of Organometallic ChemistryAuthor(s): Anand Ratnam, Sheela Kumari, Rajan Kumar, U.P. Singh, Kaushik GhoshAbstractIn this work, four ruthenium complexes [Ru(L1−4)(PPh3)Cl2](1–4) containing phenolate-imine ligands [L1−4H = condensed product of 2-(1-phenylhydrazinyl)-pyridine with different substituted salicylaldehyde, H = phenolic dissociable proton] were synthesized and characterized by different spectroscopic methods like IR and UV–visible spectral studies. Solid-state structures of complexes 1 and 2 were determined by single-...
Source: Journal of Organometallic Chemistry - Category: Chemistry Source Type: research
This study investigated the apparent reaction kinetics and degradation pathways of nitrobenzene by ozone enhanced by high gravity technology in the presence of tert-butyl alcohol, a radical scavenger. A promoted effect of ozone and high gravity technology was observed in the degradation of nitrobenzene due to the enhanced mass transfer of ozone into water by unique characteristics of high gravity technology. The second order rate constant was obtained varied from 0.732 L/(mol·s) to 5.261 L/(mol·s) at different operation parameters (temperature, initial pH value, high-gravity factor, initial nitr...
Source: Chemical Engineering and Processing: Process Intensification - Category: Chemistry Source Type: research
Publication date: 15 January 2020Source: Catalysis Today, Volume 340Author(s): Sami Rtimi, John KiwiAbstractThis review focuses on the acceleration of the bactericidal and fungicidal effects by uniform, adhesive Cu-based nanocomposites on textile and thin polymer surfaces. The acceleration of the bacterial inactivation kinetics mediated by Cu, TiO2/Cu and ZrO2-TiO2-Cu films in aerobic and anaerobic media is discussed for Gram negative, Gram positive bacteria and fungi. The Cu induced bacterial inactivation kinetics in the dark was observed to occur within the minute range for diverse bacteria. The characterization of the i...
Source: Catalysis Today - Category: Chemistry Source Type: research
Analyst, 2019, Accepted Manuscript DOI: 10.1039/C9AN01753D, PaperKunhao Qin, Dongfang Zhang, Yafang Ding, Xiaodan Zheng, Yingying Xiang, Jianhao Hua, Qi Zhang, Xiuling Ji, Bo Li, Yunlin Wei Carbon dots (CDs) has broad prospective applications in various fields, and expanding the applications of fluorescent CDs, especially for CDs derived from bacteria, is a major research goal. In this... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - Category: Chemistry Authors: Source Type: research
CONCLUSIONS In conclusion, our results showed that Carnosic acid has the potential to inhibit cancer cell growth in A-549 lung cancer cells by activating apoptotic death, inhibiting cell migration and invasion and suppressing PI3K/AKT/m-TOR signaling pathway. PMID: 31631173 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
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