Serum Rheumatoid Factor Levels at Acute Phase of Ischemic Stroke are Associated with Poststroke Cognitive Impairment
Background: The effect of serum rheumatoid factor (RF) on poststroke cognitive impairment remains unknown. We aimed to investigate the association of serum RF in the acute phase with cognitive impairment at 3 months after ischemic stroke onset. Methods: Our study was based on a random sample from the China Antihypertensive Trial in Acute Ischemic Stroke, a total of 582 patients from 7 of 26 participating sites of the trial with serum RF levels were included in this analysis. Cognitive impairment was defined as Mini-Mental State Examination less than 27 or Montreal Cognitive Assessment less than 25.
Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Zhengbao Zhu, Lihua Chen, Daoxia Guo, Chongke Zhong, Aili Wang, Xiaoqing Bu, Tan Xu, Jianhui Zhang, Zhong Ju, Libing Guo, Jintao Zhang, Dong Li, Chung-Shiuan Chen, Jing Chen, Yonghong Zhang, Jiang He Source Type: research