Three new limonene-derived bis-monoterpenoids from the aerial parts of Illigera cordata

Publication date: April 2019Source: Phytochemistry Letters, Volume 30Author(s): Min Zhou, Miao Dong, Xiao-Li Zeng, Xiang-Zhong HuangAbstractFrom the aerial parts of Illigera cordata, cordatins A–C (1–3), three limonene-derived bis-monoterpenoids plausibly biosynthesized via hetero-Diels-Alder cyclization and further sequential hydrolyses of monoterpene precursors, together with one known analogue (4), were isolated. The structures, including absolute configurations, were established by spectroscopic analysis and confirmed by X-ray crystallographic analysis of 5 (the common hydrolytic product of 1–4). All the isolated compounds were evaluated for their anti-inflammatory activity. However, no significant activities were detected at concentrations up to 25 μM.Graphical abstract
Source: Phytochemistry Letters - Category: Chemistry Source Type: research
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