Towards equity in immunisation.

Towards equity in immunisation. Euro Surveill. 2019 Jan;24(2): Authors: Boyce T, Gudorf A, de Kat C, Muscat M, Butler R, Habersaat KB Abstract In the World Health Organization (WHO) European Region, differences in uptake rates of routine childhood immunisation persist within and among countries, with rates even falling in some areas. There has been a tendency among national programmes, policymakers and the media in recent years to attribute missed vaccinations to faltering demand or refusal among parents. However, evidence shows that the reasons for suboptimal coverage are multifactorial and include the social determinants of health. At the midpoint in the implementation of the European Vaccine Action Plan 2015-2020 (EVAP), national immunisation programmes should be aware that inequity may be a factor affecting their progress towards the EVAP immunisation targets. Social determinants of health, such as individual and household income and education, impact immunisation uptake as well as general health outcomes - even in high-income countries. One way to ensure optimal coverage is to make inequities in immunisation uptake visible by disaggregating immunisation coverage data and linking them with already available data sources of social determinants. This can serve as a starting point to identify and eliminate underlying structural causes of suboptimal uptake. The WHO Regional Office for Europe encourages countries to make the equitable delivery of vaccinat...
Source: Euro Surveill - Category: Infectious Diseases Authors: Tags: Euro Surveill Source Type: research

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The evidence shows that people with inflammatory bowel disease are at increased risk of herpes zoster.1 The cohort study conducted by Khan et  al2 published in Clinical Gastroenterology and Hepatology revealed that vaccination for herpes zoster was associated with a decreased risk of herpes zoster among older people with inflammatory bowel disease. Khan et al found that the incidence of herpes zoster was higher for unvaccinated than vac cinated people (6.97 versus 4.09 per 1000 patient-years).2 The absolute risk reduction was about 0.288%, resulting in the number needed to treat of 347.
Source: Clinical Gastroenterology and Hepatology - Category: Gastroenterology Authors: Tags: Letter to the Editor Source Type: research
Condition:   Middle East Respiratory Syndrome Coronavirus Intervention:   Biological: ChAdOx1 MERS Sponsors:   King Abdullah International Medical Research Center;   University of Oxford Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
This NIHR Signal says that the risk of shingles is about 10% per year in adults after autologous stem cell transplant. The evidence summary indicates that two doses of deactivated herpes zoster vaccine could be a safe and effective way to reduce that risk by about two thirds.This effect is similar to another, heat-treated, non-live vaccine. Either vaccine could reduce the pain and need for medical treatment associated with shingles, and long-lasting complications such as post-herpetic neuralgia. It's not yet known if people need to continue taking acyclovir as well.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
Officials have restarted the distribution of a Flu vaccine for one million children following “concerning delays”.
Source: HSJ - Category: UK Health Source Type: news
Publication date: 19 November 2019Source: Cell Reports, Volume 29, Issue 8Author(s): Wiebke Hartmann, Marie-Luise Brunn, Nadine Stetter, Nicola Gagliani, Franziska Muscate, Stephanie Stanelle-Bertram, Gülsah Gabriel, Minka BreloerSummaryHelminth parasites infect more than a quarter of the human population and inflict significant changes to the immunological status of their hosts. Here, we analyze the impact of helminth infections on the efficacy of vaccinations using Litomosoides sigmodontis-infected mice. Concurrent helminth infection reduces the quantity and quality of antibody responses to vaccination against seaso...
Source: Cell Reports - Category: Cytology Source Type: research
Publication date: 19 November 2019Source: Cell Reports, Volume 29, Issue 8Author(s): Chulwoo Kim, Rohit R. Jadhav, Claire E. Gustafson, Megan J. Smithey, Alec J. Hirsch, Jennifer L. Uhrlaub, William H. Hildebrand, Janko Nikolich-┼Żugich, Cornelia M. Weyand, Jörg J. GoronzySummaryGeneration of protective immunity to infections and vaccinations declines with age. Studies in healthy individuals have implicated reduced miR-181a expression in T cells as contributing to this defect. To understand the impact of miR-181a expression on antiviral responses, we examined LCMV infection in mice with miR-181ab1-deficient T&nbs...
Source: Cell Reports - Category: Cytology Source Type: research
The modified vaccinia Ankara (MVA) vaccine protected against variola infection among members of the U.S. Army, and did not raise safety concerns, the pivotal trial revealed.Reuters Health Information
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Infectious Diseases News Source Type: news
Authors: Gill US, Battisti A, Kennedy PT Abstract Introduction: The availability of a preventative vaccine, interferon and nucleos(t)ide analogues have provided progress in the control of chronic hepatitis B (CHB). Despite this it remains a major contributor to global morbidity and mortality. Developments in our understanding of the pathogenesis of CHB and the emergence of new therapies are paving the way, as we move towards HBV cure.Areas covered: We performed bibliographical searches of online databases to review the literature regarding conventional disease phases of CHB. We provide the latest evidence challengi...
Source: Expert Review of Anti-Infective Therapy - Category: Infectious Diseases Tags: Expert Rev Anti Infect Ther Source Type: research
Polio cases around have declined globally by more than 99 percent since 1988, but the type 1 poliovirus remains endemic in Pakistan and Afghanistan, where it has made a comeback this year and infected 102 people. Credit: Ashfaq Yusufzai/IPS By James ReinlUNITED NATIONS, Nov 20 2019 (IPS) Efforts to wipe polio off the face of the planet took a step forward this week, with a multibillion-dollar fundraiser in the Middle East helping eradication schemes tackle a virus that disproportionately kills and cripples children in poor countries. Donor governments and philanthropists pledged $2.6 billion on Tuesday in Abu Dhabi to...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Aid Asia-Pacific Development & Aid Featured Global Headlines Health IPS UN: Inside the Glasshouse Poverty & SDGs Regional Categories TerraViva United Nations polio eradication World Health Organization (WHO) Source Type: news
-- The chickenpox vaccine is the best way to prevent chickenpox, says the U.S. Centers for Disease Control and Prevention. Since the start of the U.S. chickenpox vaccination program, there has been a 90 percent drop in cases of chickenpox, the...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
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