Ceftolozane-tazobactam pharmacokinetics during extracorporeal membrane oxygenation in a lung transplant recipient.

Ceftolozane-tazobactam pharmacokinetics during extracorporeal membrane oxygenation in a lung transplant recipient.
Antimicrob Agents Chemother. 2019 Jan 14;:
Authors: Arena F, Marchetti L, De Angelis LH, Maglioni E, Contorni M, Cassetta MI, Novelli A, Rossolini GM
Abstract
Ceftolozane-tazobactam (C/T) pharmacokinetics during extracorporeal membrane oxygenation (ECMO) has not been previously studied. In this work we report on the C/T plasmatic levels in a lung transplant (LTX) recipient during ECMO, treated with C/T (i.v., 2 g ceftolozane and 1 g tazobactam, every 8 hours]) for a Pseudomonas aeruginosa pulmonary infection.
PMID: 30642936 [PubMed - as supplied by publisher]

Source: Antimicrobial Agents and Chemotherapy - January 14, 2019 Category: Microbiology Authors: Arena F, Marchetti L, De Angelis LH, Maglioni E, Contorni M, Cassetta MI, Novelli A, Rossolini GM Tags: Antimicrob Agents Chemother Source Type: research