Glycyrrhizin, a High-Mobility Group Box 1 Inhibitor, Improves Lipid Metabolism and Suppresses Vascular Inflammation in Apolipoprotein E Knockout Mice

Conclusions: Our findings indicate that the attenuation of atherosclerotic lesions inApoe–/– mice by GLY might be associated with the amelioration of lipid metabolism abnormalities, inhibition of HMGB1 expression, and alterations in the Treg/Th17 ratio.J Vasc Res 2018;55:365 –377
Source: Journal of Vascular Research - Category: Research Source Type: research