DBT finds more invasive, early-stage cancers
Digital breast tomosynthesis (DBT) finds 13% more invasive and early-stage...Read more on AuntMinnie.comRelated Reading: Are better clinical results from DBT worth the cost? DBT betters mammo performance in screening, diagnosis Ultrasound after DBT obviates diagnostic 2D mammo DBT maintains high performance over time DBT doesn't hurt screening throughput
Authors: De Luca S, Fiori C, Bollito E, Garrou D, Aimar R, Cattaneo G, De Cillis S, Manfredi M, Tota D, Massa F, Passera R, Porpiglia F Abstract BACKGROUND: To evaluate if multiparametric magnetic resonance (mpMRI)- transrectal ultrasound (TRUS) fusion targeted biopsy (TBx) versus untargeted standard biopsy (SBx) may decrease the rate of pathological upgrading of Gleason score (GS) 3+4 prostate cancer (PCa) at radical prostatectomy (RP). We also evaluated the impact of percent pattern 4 and cribriform glands at biopsy in the risk of GS 3 + 4 = 7 upgrading. METHODS: 301 patients with GS 3+4 PCa on biopsy (159 SB...
CONCLUSION: These updated recommendations should assist French speaking urologists for their management of kidney cancers. PMID: 31610874 [PubMed - in process]
CONCLUSIONS: A rigorous use of classifications is mandatory to define staging since initial diagnosis. Applying treatments based on these classifications leads to excellent survival rates (99 % in CSI, 85 % in CSII+). PMID: 31610870 [PubMed - in process]
Digital breast tomosynthesis (DBT) has a higher cancer detection rate compared...Read more on AuntMinnie.comRelated Reading: Synthesized 2D mammography identifies smaller lesions Ultrasound after DBT helpful in women with dense tissue Is screening with DBT worth the additional cost? DBT detects same tumor subtypes as digital mammography DBT finds more cancers in dense breast tissue
ConclusionsThis work has demonstrated a significant correlation between the degree of lesion enhancement in CESM and malignancy. Quantitative analysis of enhancement levels in CESM can distinguish between invasive cancers and benign or in situ lesions.Key Points• There is a possibility of quantitative assessment of contrast enhancement in CESM.• Correlation between quantitative assessment of contrast enhancement in CESM and histopathology was observed.
AbstractScreening for pancreatic cancer (PC) in high-risk groups aimed to detect early cancers is currently done only in the research setting, and data on psychological outcomes of screening in these populations is scarce. To determine the psychological impact of a national Australian pancreatic screening program, a prospective study was conducted using validated psychological measures: impact of events scale (IES), psychological consequences questionnaire (PCQ) and the cancer worry scale. Measures were administered at baseline, 1-month and at 1-year post-enrolment and correlations with abnormal endoscopic ultrasound (EUS)...
CONCLUSIONS: ROSE diagnosis has a high concordance with the final diagnosis. PMID: 31618415 [PubMed - as supplied by publisher]
The differential diagnosis of fibroids could be challenging with other uterine masses including adenomyomas or uterine cancers and sarcomas. Minimally Invasive procedures including morcellation mandates a thorough imaging and if possible histologic analyses. To date such a pathologic approach has a very poor accuracy, even conducted under ultrasound, MRI or hysteroscopic guidance. A targeted biopsy requires the development of state of the art imaging and robotics to enable a secure, reproducible, and accurate sampling.
Abstract International guidelines dictate that magnetic resonance imaging (MRI) should be part of the primary standard work up of patients with rectal cancer because MRI can accurately identify the main risk factors for local recurrence and stratify patients into a differentiated treatment. The role of endoscopic ultrasound (EUS) is restricted to staging of superficial tumors because EUS is able to differentiate between T1 and T2 rectal cancer. Recent guidelines recommend the addition of diffusion-weighted (DWI) MRI to clinical and endoscopic assessment of response to preoperative radiochemotherapy (RCT). MRI...
Abstract PURPOSE: Immunotherapy promises unprecedented benefits to cancer patients. However, the majority of cancer types, including high-risk neuroblastoma remain immunologically unresponsive. High intensity focused ultrasound (HIFU) is a non-invasive technique that can mechanically fractionate tumors, transforming immunologically 'cold' tumors into responsive 'hot' tumors. EXPERIMENTAL DESIGN: We treated