Th17 pathway genes polymorphisms in Algerian patients with systemic sclerosis.

CONCLUSION: The study revealed that IL-17F and IL-21 genes were associated with systemic sclerosis (SSc) susceptibility and that IL-17A, IL-17F, IL-21 and IL-23R genes influence the clinical and immunological features, which suggest the implication of TH17 cells in SSc pathogenesis. PMID: 30641535 [PubMed - in process]
Source: Acta Reumatologica Portuguesa - Category: Rheumatology Authors: Tags: Acta Reumatol Port Source Type: research