Diagnostic accuracy of presepsin for sepsis by the new Sepsis-3 definitions

Early diagnosis of sepsis in the Emergency Department and intensive care unit (ICU) is important when treating septic patients. Novel biomarkers of sepsis have been developed and are being widely adopted in clinical settings. Among them, procalcitonin (PCT) has been widely used as biomarker in septic patients but has limited specificity. It increases transiently in patients with non-septic conditions and systemic inflammatory response syndromes (SIRS) (e.g., trauma, surgery, and heatstroke) [1].

Source: The American Journal of Emergency Medicine - January 15, 2019 Category: Emergency Medicine Authors: Tomonori Yamamoto, Tetsuro Nishimura, Shinichiro Kaga, Kenichiro Uchida, Yosuke Tachibana, Maiko Esaki, Wakaba Fukushima, Kyoko Kondo, Yasumitsu Mizobata Source Type: research