Regulation of acetate metabolism and coordination with the TCA cycle via a processed small RNA [Microbiology]

Bacterial regulatory small RNAs act as crucial regulators in central carbon metabolism by modulating translation initiation and degradation of target mRNAs in metabolic pathways. Here, we demonstrate that a noncoding small RNA, SdhX, is produced by RNase E-dependent processing from the 3′UTR of the sdhCDAB-sucABCD operon, encoding enzymes of the...

Source: Proceedings of the National Academy of Sciences - January 15, 2019 Category: Science Authors: Francois De Mets, Laurence Van Melderen, Susan Gottesman Tags: PNAS Plus Source Type: research