Effects of CYP2C8 and SLCO1B1 genetic polymorphisms on repaglinide pharmacokinetics: A systematic review and meta-analysis.

CONCLUSION: The current systematic review and meta-analysis indicated that the genotype of CYP2C8, but not SLCO1B1, may affect repaglinide pharmacokinetics. However, because of the comparatively insufficient number of published studies included, our conclusions require support from additional studies.
PMID: 30636597 [PubMed - as supplied by publisher]

Source: Current Drug Metabolism - January 10, 2019 Category: Drugs & Pharmacology Authors: Zhou S, Xiang Q, Mu G, Ma L, Chen S, Xie Q, Zhang Z, Cui Y Tags: Curr Drug Metab Source Type: research