Alteplase and DNase for the treatment of pleural empyema in rats

ConclusionsAlteplase, DNase and alteplase + DNase changed significantly physical and chemical properties of experimental empyema at fibrinopurulent phase: alteplase reduced molecular size larger than 135 nm and DNase reduced viscosity.
Source: Pulmonary Pharmacology and Therapeutics - Category: Respiratory Medicine Source Type: research