Odds Of Dying From Accidental Opioid Overdose In US Surpass Those Of Dying In Car Accident
(CNN) — For the first time on record the odds of accidentally dying from an opioid overdose in the United States are now greater than those of dying in an automobile accident. The grim finding comes from the National Safety Council which analyzed preventable injury and fatality statistics from 2017. The NSC also found the lifetime odds of death for this form of overdose were greater than the risk of death from falls, pedestrian incidents, drowning and fire. Examining a variety of federal and state data the NSC found the lifetime odds of dying from an accidental opioid overdose were 1 in 96. For motor vehicle accidents the odds were 1 in 103 and 1 in 114 for falls. The lifetime odds of suicide were greater, at 1 in 88. The NSC highlights, however, that the odds given are statistical averages over the whole US population and do not necessarily reflect the chances of death for a particular person from a particular external cause. In addition they are lifetime odds, based on dividing the one-year odds by the life expectancy of a person born in 2017. In 2017 preventable injury deaths were 169,936 — an increase of 5.3% from the year before and a 96% increase compared to the figures in 1992. The organization aims to highlight these numbers in a bid to help prevent future deaths from preventable causes. “For too long, preventable deaths and injuries have been called ‘accidents,’ implying unavoidable acts of God or fate that we are powerless to stop. This...
Publication date: Available online 24 September 2020Source: Journal of Theoretical BiologyAuthor(s): Roberta Coletti, Andrea Pugliese, Luca Marchetti
Publication date: Available online 24 September 2020Source: Advances in Biological RegulationAuthor(s): Nilufar Rahimova, Mariana Cooke, Suli Zhang, Martin J. Baker, Marcelo G. Kazanietz
Publication date: Available online 24 September 2020Source: Biochimica et Biophysica Acta (BBA) - BiomembranesAuthor(s): Aurélie H. Benfield, Sira Defaus, Nicole Lawrence, Stephanie Chaousis, Nicholas Condon, Olivier Cheneval, Yen-Hua Huang, Lai Yue Chan, David Andreu, David J. Craik, Sónia Troeira Henriques
Chem. Commun., 2020, Advance Article DOI: 10.1039/D0CC04999A, CommunicationChristina A. McConville, Yunwen Tao, Hayden A. Evans, Benjamin A. Trump, Jonathan B. Lefton, Wenqian Xu, Andrey A. Yakovenko, Elfi Kraka, Craig M. Brown, Tom če Runčevski Here we report the phase diagram of acetonitrile and benzene with the focus on a 1 : 3 acetonitrile : benzene cocrystal relevant to mineralogy of Titan, Saturn's moon. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Abstract Endometrial cancer (EC) harboring heterozygous POLE proofreading inactivating mutations (POLE-exo*) is associated with an increased number of somatic mutations that result in a distinctive anti-tumor immune response. However, the consequences of such POLE mutations in the context of the missing wild-type allele have not yet been described in endometrial tumors. A 72-year-old woman harboring a germline monoallelic frameshift mutation (p.Pro269fsTer26) in POLE was diagnosed with an EC having a somatic heterozygous mutation in the exonuclease domain of POLE (S459F). Targeted gene sequencing revealed an ultramutated p...
Publication date: Available online 24 September 2020Source: Safety and Health at WorkAuthor(s): Selin Kim, Wonjeong Jeong, Sung-In Jang, Eun-Cheol Park, Sohee Park
CONCLUSION: frail elderly caregivers with depressive symptoms had a worse perception of quality of life. PMID: 32965434 [PubMed - in process]
CONCLUSION: The study identified both a high prevalence of xerostomia regardless of the chemotherapy used and the need to create protocols to improve the quality of life of these patients. PMID: 32965427 [PubMed - in process]
CONCLUSION: Celiac individuals with anxiety and depression frameworks presented a higher frequency of Perceived clinical condition, Insufficient social support (psychoaffective factors) and Daily obstacles for maintaining a gluten-free diet (daily-life factor). PMID: 32965317 [PubMed - in process]
CONCLUSION: The findings of this study make it possible to assess anxiety and depression in caregivers of dependent elderly people, making it possible, through these parameters, to view the profile and care demands of this population. PMID: 32965315 [PubMed - in process]
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