Characterization of a highly specific monoclonal antibody against human aldo-keto reductase AKR1C3

In this report, a highly specific monoclonal antibody for AKR1C3, 10B10, was developed and characterized. Compared to other AKR1C3 antibodies, 10B10 is highly specific and sensitive to AKR1C3 in multiple assay formats. Thus, 10B10 will be a valuable tool for the clinical development of AKR1C3 targeting therapeutics and the study of AKR1C3 biology.
Source: Steroids - Category: Drugs & Pharmacology Source Type: research