Modulation of proinflammatory cytokines and enzymes by polyherbal formulation Guggulutiktaka ghritam

ConclusionThe study revealed that GTG is a leukotriene and cytokine inhibitor. The inhibition in the production of cytokines may be due to the down-regulation of genes for TNF-α and IL-1β. The study provides a scientific validation on the possible anti-inflammatory mechanism of action of this traditionally used medicine. Identification of bioactive molecules would aid in developing newer therapeutics for control of chronic inflammation.Graphical abstract
Source: Journal of Ayurveda and Integrative Medicine - Category: Complementary Medicine Source Type: research