It Takes a Matured mAb to Treat Ebolavirus Infection.

It Takes a Matured mAb to Treat Ebolavirus Infection. Cell Host Microbe. 2019 Jan 09;25(1):10-12 Authors: Patel A, Weiner DB Abstract Pan-Ebolavirus immunotherapy would provide a rapid-response treatment during Ebola virus outbreaks. In this issue of Cell Host &Microbe, Wec et al. (2019) and Bornholdt et al. (2019) optimize the MBP134 mAb cocktail through antibody affinity maturation, improving its protective efficacy against three Ebolaviruses: EBOV, SUDV, and BDBV. PMID: 30629912 [PubMed - in process]
Source: Cell Host and Microbe - Category: Microbiology Authors: Tags: Cell Host Microbe Source Type: research

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[Daily News] THE Ministry of Health, Community Development, Gender and Children (MHCDGC), has conducted training to various health stakeholders, including Rural Community Health Workers (RCHW) from nine regions as part of efforts to intensify preventive measures against Ebola virus.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
by C éline Couturier, Atsuhiko Wada, Karen Louis, Maxime Mistretta, Benoit Beitz, Moriba Povogui, Maryline Ripaux, Charlotte Mignon, Bettina Werle, Adrien Lugari, Delphine Pannetier, Sabine Godard, Anne Bocquin, Stéphane Mely, Ismaël Béavogui, Jean Hébélamou, David Leuenberger, Philippe Leissner, T akeshi Yamamoto, Patrick Lécine, Christophe Védrine, Julie Chaix Hemorrhagic fever outbreaks are difficult to diagnose and control in part because of a lack of low-cost and easily accessible diagnostic structures in countries where etiologic agents are present. Furthermore, ...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
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Source: WHO Disease Outbreaks - Category: Infectious Diseases Tags: news Source Type: news
Source: National Institutes of Health (NIH). Published: 1/14/2020. This one-hour, 44-minute presentation discusses how the National Institutes of Health (NIH) has been at the forefront in the global effort to prevent the spread of Ebola virus. NIH staff were deployed in western Africa during the 2015-2016 Ebola outbreak to provide primary care to those infected, and Ebola patients were received at the NIH Clinical Center. For many years prior, NIH scientists studied the natural reservoirs of emerging viruses such as Ebola virus and have elucidated the biology of Ebola virus infection, which has informed the creation of in...
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - Category: International Medicine & Public Health Source Type: news
(INSERM (Institut national de la sant é et de la recherche m é dicale)) Public health efforts successfully stopped human-to-human transmission of Ebola virus in West Africa in 2016 after the worst Ebola outbreak in history. Pursuing and intensifying efforts to develop a safe and effective vaccination strategy against Ebola virus disease, with durable protection in all populations, including children, is vital.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
ole Lackemeyer Jesse Steffens Adrienne Kimmel Carly Garvey Holly Bloomfield Christiana Blair Bali Singh Sina Bavari Tomas Cihlar Danielle Porter Recent Ebola virus (EBOV) outbreaks in West Africa and the Democratic Republic of the Congo have highlighted the urgent need for approval of medical countermeasures for treatment and prevention of EBOV disease (EVD). Until recently, when successes were achieved in characterizing the efficacy of multiple experimental EVD therapeutics in humans, the only feasible way to obtain data regarding potential clinical benefits of candidate therapeutics was by conductin...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
L, Merrill R Abstract On August 1, 2018, the Democratic Republic of the Congo (DRC) declared its 10th Ebola virus disease (Ebola) outbreak in an area with a high volume of cross-border population movement to and from neighboring countries. The World Health Organization (WHO) designated Rwanda, South Sudan, and Uganda as the highest priority countries for Ebola preparedness because of the high risk for cross-border spread from DRC (1). Countries might base their disease case definitions on global standards; however, historical context and perceived risk often affect why countries modify and adapt definitions over ...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
Abstract Tailoring communicable disease preparedness and response strategies to unique population movement patterns between an outbreak area and neighboring countries can help limit the international spread of disease. Global recognition of the value of addressing community connectivity in preparedness and response, through field work and visualizing the identified movement patterns, is reflected in the World Health Organization's declaration on July 17, 2019, that the 10th Ebola virus disease (Ebola) outbreak in the Democratic Republic of the Congo (DRC) was a Public Health Emergency of International Concern (1)....
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
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Source: Guardian Unlimited Science - Category: Science Authors: Tags: Epidemics Infectious diseases Health China Sars Ebola Asia Pacific Society World news World Health Organization Science Medical research Microbiology Source Type: news
The Democratic Republic of Congo (DRC) is experiencing its 10th Ebola virus disease outbreak in an area with a high volume of cross-border population movement.
Source: CDC Morbidity and Mortality Weekly Report - Category: American Health Tags: Ebola Virus Disease MMWR Morbidity & Mortality Weekly Report Outbreaks Health Communication Source Type: news
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