Alobar holoprosencephaly detected in a  9-week embryo

A 37-year-old woman with a spontaneous pregnancy presented for routine early ultrasound. Transvaginal scanning demonstrated a single live embryo with a crown −rump length of 25 mm, equivalent to 9 weeks’ gestation. In normal embryos, lateral cerebral ventricles are visible by 9 weeks (Figure 1). In this patient, a single anterior cerebral monoventricle (MV) was detected on 2-dimensional ultrasound (Figure 2). Three-dimensional ultrasound (Figure 3 ) with volume-rendered imaging of the ventricular system (Figure 4) confirmed alobar holoprosencephaly.

Source: American Journal of Obstetrics and Gynecology - January 6, 2019 Category: OBGYN Authors: Simon Meagher, Lisa Hui Tags: Images in Obstetrics Source Type: research