Rare Antibiotic-Resistant Infection Found in Wyoming Patient Rare Antibiotic-Resistant Infection Found in Wyoming Patient

Enterobacteriaceae with a rare antibiotic-resistant gene, mcr-1, was isolated in a Wyoming hospital patient, who does not appear to have acquired the infection at the hospital.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

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Conclusions: Our findings suggest the need for a comprehensive, multipronged policy response particularly at the time when the antibiotic pipeline is nearly empty. We recommend thoughtful, integrated infection prevention and control strategies to address the immediate and long-term threats of AR in Bahrain and the GCC. PMID: 31110624 [PubMed]
Source: Oman Medical Journal - Category: Middle East Health Tags: Oman Med J Source Type: research
This study aimed to determine the dynamics of colonization with antimicrobial-resistant Gram-negative bacteria amongst patients in a neonatal intensive care unit (NICU) in Thailand. From 97 enrolled patients, 52% were colonized by an extended-spectrum β-lactamase (ESBL) organism at some point during their stay and 64% were colonized by a carbapenem-resistant organism. Rapid acquisition of ESBL-positive and carbapenem-resistant organisms was found. Once colonized with an antibiotic-resistant organism, patients remained colonized for the remainder of their NICU stay.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
Publication date: Available online 22 May 2019Source: Journal of Global Antimicrobial ResistanceAuthor(s): Vanessa Silva, Francisco Almeida, Adriana Silva, Susana Correia, José António Carvalho, Ana Paula Castro, Eugénia Ferreira, Vera Manageiro, Manuela Caniça, Gilberto Igrejas, Patrícia Poeta
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
Publication date: Available online 22 May 2019Source: Nanomedicine: Nanotechnology, Biology and MedicineAuthor(s): Dickson K. Kirui, Gregor Weber, Jennifer Talackine, Nancy J. MillenbaughAbstractThe growing prevalence of biofilm-associated multi-drug resistant (MDR) bacteria necessitates the innovation of non-traditional approaches to improve the effectiveness of mainstay antibiotics. Here, we evaluated the use of gold nanoparticle (GNP)-targeted pulsed laser therapy to enhance antibiotic efficacy against in vitro methicillin-resistant Staphylococcus aureus (MRSA) and MDR Pseudomonas aeruginosa biofilms. Treatment with ant...
Source: Nanomedicine: Nanotechnology, Biology and Medicine - Category: Nanotechnology Source Type: research
Superbugs are bacteria that can beat modern medicine's most powerful drugs. So doctors are racing to find new ways to fight back, such as developing "living antibiotics."(Image credit: Rob Stein/NPR)
Source: NPR Health and Science - Category: Consumer Health News Authors: Source Type: news
Authors: Bassetti M, Peghin M, Castaldo N, Giacobbe DR Abstract INTRODUCTION: Acute bacterial skin and skin-structure infections (ABSSSI) may develop in both in-patients and out-patients, possibly with a severe clinical presentation. Since most phase 3 randomized clinical trials have shown non-inferiority in efficacy across different agents, considerations regarding their different safety profiles inevitably play a crucial role in the everyday choice about which of them should be employed for the treatment of ABSSSI. Areas covered: In this review the authors discuss the safety profile of different treatment options...
Source: Expert Opinion on Drug Safety - Category: Drugs & Pharmacology Tags: Expert Opin Drug Saf Source Type: research
The rapid increase in antibiotic-resistant bacteria has emphasised the urgent need to identify new treatments for bacterial infections. One attractive approach, avoiding the need for expensive and time-consuming clinical trials, is to re-purpose existing clinically-approved compounds for use as antibacterial agents. Nucleoside analogues are commonly used for treating viral and fungal infections, as well as for treating cancers, but have received relatively little attention as treatments for bacterial infections. However a significant number of clinically-approved derivatives of both pyrimidines and purines including haloge...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Conclusion: PVL expression is high among clinical S. aureus strains among Gambian patients. Reporting of PVL-SA clinical infections is necessary to enable the monitoring of the clinical impact of these strains in the population and guide prevention of the spread of virulent PVL-positive CA-MRSA strains.
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Among the major drivers of the Antimicrobial Resistance crisis is the misuse and overuse of antibiotics in livestock and feed. Credit: Germán Miranda/IPS. By Tharanga YakupitiyageUNITED NATIONS, May 21 2019 (IPS) Antimicrobial resistance is quickly becoming a global crisis and risks reversing a century of progress in health. Some organisations have already geared up and are tackling the issue from its roots. In a new report, the United Nations Interagency Coordination Group (IACG) on Antimicrobial Resistance estimates that antibiotic resistance could cause 10 million deaths each year by 2050. Already, drug-resistan...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Development & Aid Featured Global Headlines Health IPS UN: Inside the Glasshouse North America Regional Categories Sustainability TerraViva United Nations Antimicrobial resistance (AMR) WHO Source Type: news
Engineered phages were used to treat a teenager ’s life-threatening antibiotic-resistant infection. The approach could be used to combat otherwise untreatable infections.
Source: NIH Research Matters from the National Institutes of Health (NIH) - Category: Consumer Health News Source Type: news
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