Medical News Today: What is an alanine aminotransferase (ALT) blood test?

An alanine aminotransferase (ALT) test helps doctors diagnose problems with the liver, such as hepatitis or liver disease. Learn more about the ALT blood test in this article.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

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In conclusion, our study demonstrates that orexin A peptide possesses a protective role against HBx-mediated cytotoxicity and inflammation in hepatocytes. PMID: 31106596 [PubMed - in process]
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
Authors: Fonseca F, Kulkarni B, Hastak M, Kumaran V, Varma V, Kapoor S Abstract INTRODUCTION AND AIM: 1. Study of liver explants - Etiologic types of end-stage chronic liver disease (ESCLD) and acute liver failure (ALF) in adults and children. 2. Assessment of donor steatosis and incidental granulomas. 3. Post-transplant liver biopsies. MATERIAL AND METHODS: Specimens of 180 explant hepatectomies, 173 donor wedge and 30 core liver biopsies, and 58 post transplant liver biopsies received in our department from April 2013 to March 2017. RESULTS: 1. Most common causes of ESCLD in adults were: alcohol related (...
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
CONCLUSIONS: Dynamic assessment of prognostic scores better predicts outcome. ALFED model performs better than MELD, MELD, MELD-Na, CLIF-C ACLF scores and KCH criteria for predicting outcome in viral hepatitis-related ALF. PMID: 31103144 [PubMed - in process]
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
A large European study now suggests that many diagnoses of cirrhosis and liver cancer come too late, and that diabetes might be an independent risk factor.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news
The GGT test is a simple blood test that helps doctors diagnose liver or bile duct damage. Learn more about the GGT test, normal and abnormal ranges, and the procedure, here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news
Conclusions: Our results confirm the tight link between NAFLD and metabolic complications, suggesting prediabetes as a new risk factor of steatosis. SCCA-IgM does not seem to have a role in the identification and prognosis of NAFLD.Obes Facts 2019;12:291 –306
Source: Obesity Facts - Category: Eating Disorders & Weight Management Source Type: research
Analyst, 2019, Accepted Manuscript DOI: 10.1039/C9AN00179D, PaperJialong Fan, Liqun Yuan, Qingxin Liu, Chunyi Tong, Feng Xiao, Wenmiao Wang, Bin Liu, Xuanming Liu Hepatitis C virus (HCV) is a major cause of chronic liver disease, which affected the 2-3 % world population. Until now, early detection of HCV is a great challenge especially... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - Category: Chemistry Authors: Source Type: research
AbstractPurpose of ReviewThe lymphatic network plays a major role in maintaining tissue fluid homeostasis. Therefore, several pathological conditions associated with edema formation result in deficient lymphatic function. However, traditionally, the lymphatic system has been underestimated until recent years when it has been noticed the importance of this system in chronic liver disease. This review highlights the knowledge of lymphatic biology in the context of portal hypertension and liver cirrhosis.Recent FindingsAmong different roles of lymphatic system in liver disease, two remarkable ones are the contribution in asci...
Source: Current Hepatitis Reports - Category: Infectious Diseases Source Type: research
This study explored the anti-inflammatory influence of Emodin on LPS-triggered liver injury in vitro and in vivo. In vitro, we discovered that LPS treatment triggered L-02 cell and primary hepatocyte inflammatory injury. Emodin weakened the LPS-triggered cell inflammatory injury and NF-κB pathway activation. Emodin alleviated LPS-stimulated decrease of miR-145 expression. Moreover, miR-145 participated in the regulation of pro-inflammatory factors expression and negatively regulated IRAK1. Besides, IRAK1 exert regulatory roles in the activation of NF-κB pathway. In vivo, we found that Emodin pre-treatment weake...
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
Abstract Giant cell hepatitis (GCH) is a rare diagnosis in adults that is found in 0.25% of liver biopsies. GCH has been associated with multiple causes including drugs (6-mercaptopurine, methotrexate), toxins, viruses and autoimmune. GCH has been described in few patients with chronic lymphocytic leukemia (CLL). Here we describe three patients diagnosed with GCH thought to be related to underlying CLL and its management. All of our patients were treated with a combination of immunosuppression as well as CLL-directed therapy to address CLL and concomitant liver disease. GCH is a rare manifestation of active CLL an...
Source: Cancer Biology and Therapy - Category: Cancer & Oncology Authors: Tags: Cancer Biol Ther Source Type: research
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