A newly emerging trend of chitosan-based sensing platform for the organophosphate pesticide detection using Acetylcholinesterase-a review

Publication date: Available online 10 January 2019Source: Trends in Food Science & TechnologyAuthor(s): Hitika Patel, Deepak Rawtani, Y.K. AgrawalAbstractBackgroundOrganophosphate pesticides have been extensively used to protect the agricultural produce from being damaged by the pests while growing and the subsequent degradation in its quality. However, in the process of doing so, the pesticides and their degradation products, enter the soil and water and start accumulating in the food products. On the consumption of such pesticide infected food products, Acetylcholinesterase is inhibited, which can be potentially damaging to the central nervous system of human beings. Acetylcholinesterase plays a pivotal role in the orderly functioning of the nervous system and in case of its failure to do so; there is a plausibility of deteriorating health in the individual.Scope and approachThis review gives an insight into the recent approaches towards the rapid sensing of the deleterious pesticides. Numerous sensing platforms, comprising of chitosan as the key element of the immobilization matrix for the subsequent binding of acetylcholinesterase have been highlighted in this study. Chitosan plays the decisive role by aiding in the maintenance of the activity of immobilized Acetylcholinesterase.Key findings and conclusions: The acetylcholinesterase enzyme-inhibition based biosensors pave the way for a speedy and feasible detection of the organophosphate pesticides present in the food art...

Source: Trends in Food Science and Technology - January 11, 2019 Category: Food Science Source Type: research