Is Daily Vitamin D a Lifesaver for COPD Patients?
Taking vitamin D supplements was associated with a 45 percent reduction in lung attacks among patients who were deficient in vitamin D, but there was no reduction among patients with higher vitamin D levels, the investigators found.
(MedPage Today) -- Vitamin D pills almost halved exacerbation risk in vitamin D-deficient, COPD patients
(MedPage Today) -- But only in patients with baseline deficiency
(Queen Mary University of London) Vitamin D supplements have been found to reduce the risk of potentially fatal lung attacks in some chronic obstructive pulmonary disease (COPD) patients, according to a study led by Queen Mary University of London.
Conclusions: COPD women, as compared with men, had similar distribution of disease severity and more exacerbations, despite milder smoking history. Women had higher prevalence of anxiety, valvular disease, thyroid disease, but lower prevalence of ischemic heart and cerebral disease and neoplastic disease.
Aims of study: To determine prevalence of Vitamin D deficiency &anaemia in patients admitted to hospital with acute exacerbations of COPD (AECOPD); morbidity &mortality.Methods: Retrospective study; patients admitted to hospital with acute exacberation of COPD (AECOPD). Data included: COPD severity (GOLD), admission frequency, presence of osteoporosis, walking distance (WD), laboratory values including vitamin D (VitD).Results: 125 patients, 63% female; age 73.5 (10.9)y. GOLD stage (III 27 %; IV 57 %); long-term oxygen (LTOT) 38%; chronic type 2 respiratory failure (T2RF) 56.8%. Median number of admissions/y for AE...
Conclusion: Vitamin D deficiency is more prevalent in COPD patients. However, in patients with severe exacerbation, presence of low Vitamin D did not have any impact on survival; days of hospital stay or need to mechanical ventilation.
Conclusions: We consider Vit. D a marker of inflammation that strongly correlate with the severity of BE.
Publication date: Available online 3 November 2018Source: The Journal of Steroid Biochemistry and Molecular BiologyAuthor(s): Jef Serré, Carolien Mathyssen, Tom Tanjeko Ajime, Hannelie Korf, Karen Maes, Nele Heulens, Conny Gysemans, Chantal Mathieu, Bart Vanaudenaerde, Wim Janssens, Ghislaine Gayan-RamirezAbstractChronic obstructive pulmonary disease (COPD), which is characterized by an excessive inflammatory response of the airways, is often complicated by exacerbations. Vitamin D deficiency has been associated with an increased risk for COPD and may predispose COPD patients to a higher exacerbation rate, particula...
Conclusion: Although preoperative vitD supplementation was not found to be associated with prevention of POAF in patients with vitD insufficiency, it was found to be strongly associated with prevention of POAF in those wi th vitD deficiency.