Risk of sudden cardiac death: Are coronary chronic total occlusions an additional risk factor?

Risk of sudden cardiac death: Are coronary chronic total occlusions an additional risk factor? World J Cardiol. 2018 Dec 26;10(12):250-253 Authors: Merinopoulos I, Corballis N, Eccleshall SC, Vassiliou VS Abstract Sudden arrhythmic cardiac death remains a significant, potentially reversible, cardiological challenge in terms of creating accurate risk prediction models. The current guidelines for implantable cardioverter defibrillator (ICD) therapy are mainly based on left ventricular ejection fraction despite its low sensitivity and specificity in predicting sudden cardiac death (SCD). Chronic total occlusions have been associated with increased mortality but further research is required to clarify if they should be incorporated in a risk model predicting SCD aiming to identify patients that would benefit from ICD therapy even with preserved ejection fraction. PMID: 30622683 [PubMed]
Source: World Journal of Cardiology - Category: Cardiology Authors: Tags: World J Cardiol Source Type: research
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