Blacks With HCC May Live Longer If Liver Donor Is Black Blacks With HCC May Live Longer If Liver Donor Is Black
For black Americans with hepatocellular carcinoma (HCC) treated with a liver transplant, overall survival beyond 1 year was improved if the liver donor was also a black American.Medscape Medical News
Authors: Oikonomou T, Goulis L, Doumtsis P, Tzoumari T, Akriviadis E, Cholongitas E Abstract INTRODUCTION AND AIM: Studies carried out mainly in patients with hepatocellular carcinoma (HCC), have shown the prognostic significance of albumin-bilirubin (ALBI) grade. Recently, another predictive score incorporating platelet count into ALBI, PALBI grade, was introduced in patients with HCC. AIM: We evaluated the ability of ALBI and PALBI grades in predicting the outcome (mortality / liver transplantation) of patients with stable decompensated cirrhosis with various etiology of liver diseases. MATERIAL AND METHO...
ConclusionLLR for HCC after FP is safe and feasible, and might be considered an alternative treatment of HCC for which the best treatment has not been defined yet.
American Journal of Roentgenology, Ahead of Print.
This study aimed at investigating the impact of ACR treatment on the incidence of tumor recurrence in a large European HCC-LT population.MethodsSeven hundred and eighty-one adult patients transplanted between February 1, 1985 and June 30, 2016 were retrospectively analyzed. After propensity score match, 116 patients treated for ACR using steroid boluses were compared with 115 patients who did not present any ACR or a histologic but clinical irrelevant ACR.ResultsSteroid boluses treated patients had a 18-fold higher overall incidence of HCC recurrence than those non-treated patients (16.4% vs. 0.9%; P
Semin intervent Radiol 2019; 36: 137-141 DOI: 10.1055/s-0039-1688430Percutaneous thermal ablation of hepatic tumors continues to play an integral role in the treatment of early-stage primary or secondary hepatic malignancies. Interventional radiologists must be familiar with potential complications of this procedure, associated risk factors, and methods for prevention. The authors report a devastating case of septic shock and death following percutaneous microwave ablation of a solitary hepatocellular carcinoma in a liver transplant patient with a bilioenteric anastomosis (BEA). We review the literature regarding prophylac...
CONCLUSIONS: SOF-based therapy for patients progressing to liver transplantation leads to high SVR rates, short term stability in liver function, and deactivation from the transplant list. PMID: 31103148 [PubMed - in process]
HCC incidence is still growing in Western countries.[1,2] Tumor development is frequently related to liver damage, typically caused by cirrhosis. While curative treatments (transplantation, resection, percutaneous destruction) can be proposed for small tumors, about two thirds of patients cannot receive such treatments.
Publication date: Available online 17 May 2019Source: Journal of Vascular and Interventional RadiologyAuthor(s): Tyler Sandow, John Pavlus, David Field, Eduardo Lacayo, Emil Cohen, George Lynskey, Theresa Caridi, Donna Buckley, John Cardella, Bhaskar Kallakury, James Spies, Alexander Y. KimAbstractPurposeTo evaluate tumor response to transarterial chemoembolization as well as biologic characteristics of the tumor as predictors of recurrence after transplantation in patients with hepatocellular carcinoma (HCC) who were bridged or down-staged to liver transplantation.Materials and MethodsAn institutional review board-approve...
Hepatocellular carcinoma (HCC) is the most common primary hepatic malignancy and the third most frequent cause of cancer-related deaths.[1,2] Although the prognosis of patients with advanced HCC remains poor, patients with early-stage HCC are eligible for curative treatments such as surgical resection, local ablation, and liver transplantation.[3,4] Therefore, accurate imaging diagnosis of early-stage HCC is important.
CONCLUSIONS: Our study is the first one reporting data of circulating caspase-3 levels prior to LT for HCC, and an association between high serum caspase-3 levels previously to LT and survival at first year after LT. PMID: 31084510 [PubMed - as supplied by publisher]