National Geographic Takes an Interest in Organs-on-Chips Research

Biomedical researchers at Cedars-Sinai Medical Center in Los Angeles, CA have caught the attention of National Geographic. The magazine published a special edition this month covering "The Future of Medicine" that highlights the innovative stem-cell science of Cedars-Sinai, showing how investigators there are seeking to use stem cells and organs-on-chips to tailor personalized medical treatments. The cover photo of the special issue features research being conducted at Cedars-Sinai in collaboration with Boston, MA-based Emulate, a startup developing a tissue-based technology designed to replicate human organ-level function that is used to model organs in healthy and diseased states. According to Cedars-Sinai, scientists can place copies of patients' own cells (created from their stem cells) inside transparent chips that are the size of AA batteries. Drugs then can be tested on the cells, to help doctors tailor treatment options to the individual patient. Using this technique, Cedars-Sinai has so far created functioning tissues of intestinal linings and spinal cords inside the chips, and more tissues are planned. Parkinson's disease, amyotrophic lateral sclerosis (ALS), ovarian cancer, and inflammatory bowel disease (which includes Crohn's and ulcerative colitis) are among the disorders being studied on the chip. The pioneering Patient-on-a-Chip program is a collaboration between the Cedars-Sinai Board of Governors Regenerative Medicine Institute, directed by Clive S...
Source: MDDI - Category: Medical Devices Authors: Tags: R & D Source Type: news

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While crowdfunding is helping patients gain access to conventional but costly mainstream treatment, people also use it for treatment at clinics offering alternative medicine.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
(Reuters Health) - Women with breast cancer who get newer genetic tests to estimate their risk of recurrence may not be any more anxious about their test results than their peers who get older tests that focus on fewer genes, a recent study suggests.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Macadamia nuts are a nutritious food with many potential benefits, including lowering the risk of heart disease and possibly helping prevent cancer. Learn more about the benefits of macadamia nuts, as well as some drawbacks to be aware of, here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Nutrition / Diet Source Type: news
A number of entities are energetically raising funds to invest in biotech startups that aim to treat aging in some way. Beyond the more traditionally structured venture funds, such as the Longevity Fund, and technology funds like Kizoo Technology Ventures and Felicis Ventures that are turning their attention to biotech investment, there are also private equity / business development companies such as Juvenescence and Life Biosciences. Today I'll point out recent news for those two regarding their success in raising funding. This sort of thing is one of the signs of a building initial hype cycle for the first meaningful way...
Source: Fight Aging! - Category: Research Authors: Tags: Investment Source Type: blogs
Abstract Tamoxifen (TMX) is the main drug used both in pre and postmenopausal women as adjuvant treatment for hormone receptor-positive breast cancer. An important barrier to the use of TMXis the development ofdrug resistance causedby molecular processes related to genetic and epigenetic mechanisms, such as the actions of cytochrome P450 2D6 (CYP2D6) polymorphisms and of its metabolites. The present study aimed to review recent findings related to the impact of CYP2D6 polymorphisms and how they can affect the results of TMX in breast cancer treatment. The keywords CYP2D6, tamoxifen, and breast cancer were searched in the P...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
Conclusion The present case highlights one of the less common but more serious consequences of radiotherapy for cervical cancer, which has an increasing incidence in younger women, raising concerns about the long-termconsequences of its management.
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
Good news is always welcome, especially when talking about something as serious as cancer. And there is plenty of welcome information in the American Cancer Society ’s release of our annual report on“Cancer Statistics, 2019” and its accompanying consumer-oriented version of“Cancer Facts&Figures 2019.” Among the good news in this report: A significant […]Find jobs at  Careers by  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more.
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Conditions Oncology/Hematology Source Type: blogs
Lung cancer experts say the recent decision to restrict the use of durvalumab immunotherapy to patients with high PD-L1 expression is'a lost therapeutic opportunity. 'Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
(Reuters Health) - Cancer survivors have higher-than-average rates of medical financial hardship, a U.S. study suggests.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Abstract Background: Chemotherapeutic agents of anthracyclines class and humanized monoclonal antibodies are effective treatments for breast cancer, however, they present a potential risk of cardiotoxicity. Several predictors have been recognized as predictors in the development of cardiac toxicity, and the evaluation of left ventricular segmental wall motion abnormalities (LVSWMA) has not been studied. Objective: To analyze prospectively the role of LVSWMA among echocardiographic parameters in the prediction of development of cardiotoxicity in breast cancer patients undergoing treatment with chemotherapy. Methods: Prospec...
Source: Arquivos Brasileiros de Cardiologia - Category: Cardiology Source Type: research
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