Saturated Bioisosteres of Benzene: Where to go Next?

Org. Biomol. Chem., 2019, Accepted Manuscript DOI: 10.1039/C8OB02812E, Review ArticlePavel K. Mykhailiuk The replacement of para-substituted benzenes with the saturated bioisosteres increases the potency, selectivity and metabolic stability of bioactive compounds. The current challenge for chemists is to rationally design, synthesize and... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research