Take Diabetes Into Consideration When Assessing for Glaucoma Take Diabetes Into Consideration When Assessing for Glaucoma

Diabetes and hyperglycemia are associated with thicker central corneal thickness, a relationship that could lead to overestimation of intraocular pressure, researchers warn ophthalmologists.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

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CONCLUSIONS: Oxidative stress, inflammation and autophagy are implicated in biochemical and morphological changes in these ocular tissues. The development of therapy is a major target for the management care of these ocular diseases. PMID: 30644339 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Design - Category: Drugs & Pharmacology Authors: Tags: Curr Pharm Des Source Type: research
Abstract The ocular surface is continually exposed to bacteria from the environment and traditional culture-based microbiological studies have isolated a low diversity of microorganisms from this region. The use of culture-independent methods to define the ocular microbiome, primarily involving 16S ribosomal RNA gene sequencing, has shown that the microbial communities present on the ocular surface have a greater diversity than previously reported and appear to have an immune modulating function. These molecular techniques have been used to investigate the effect of contact lens wear and disease on the microbiota ...
Source: Current Eye Research - Category: Opthalmology Authors: Tags: Curr Eye Res Source Type: research
Purpose of review To summarize the current findings on clinical retinal diseases and retinal imaging changes with dementia, focusing on Alzheimer's disease. Recent findings Studies observed that clinical retinal diseases such as age-related macular degeneration, open-angle glaucoma and diabetic retinopathy are related to dementia, but the associations are not entirely consistent. In terms of the retinal neuronal structure, multiple retinal neuronal layers are significantly thinner in Alzheimer's disease dementia, such as the parapapillary retinal nerve fiber layer (RNFL) and macular ganglion cell-inner plexiform layer...
Source: Current Opinion in Neurology - Category: Neurology Tags: NEURO-OPHTHALMOLOGY: Edited by Valérie Biousse Source Type: research
CONCLUSIONS: We detected elevated serum levels of TNF-α and TNFR2 in KPro patients. Longitudinal studies are needed to establish TNF-α and TNFR2 as serum biomarkers related to KPro surgery. PMID: 30632412 [PubMed - as supplied by publisher]
Source: Current Eye Research - Category: Opthalmology Authors: Tags: Curr Eye Res Source Type: research
Synthesis and biological evaluation of novel tris-chalcones as potent carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and α-glycosidase inhibitors. Bioorg Chem. 2019 Jan 02;85:191-197 Authors: Burmaoglu S, Yilmaz AO, Polat MF, Kaya R, Gulcin İ, Algul O Abstract A novel class of fluoro-substituted tris-chalcones derivatives (5a-5i) was synthesized from phloroglucinol and corresponding benzaldehydes. A three step synthesis method was followed for the production of these tris-chalcone compounds. The structures of the newly synthesized compounds (5a-5i) were confirmed on the basis o...
Source: Bioorganic Chemistry - Category: Chemistry Authors: Tags: Bioorg Chem Source Type: research
To estimate the 3-year incidence of blindness among diabetes patients aged ≥18 years; to compare blindness incidence rates of persons with and without diabetes; to investigate risk factors associated with diabetic retinopathy (DR), age-related macular degeneration (ARMD), glaucoma and cataract-related blindness.
Source: American Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Original Articles Source Type: research
Aniridia is a rare condition: the diagnostic feature is absence or hypoplasia of the iris, commonly with associated conditions, such as glaucoma and cataracts [1]. The prevalence of congenital aniridia ranges from 1:64,000 to 1:96,000 [2]. Approximately two thirds of aniridia cases show highly penetrant autosomal dominant inheritance [2].
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research
Publication date: Available online 30 November 2018Source: Journal of Ginseng ResearchAuthor(s): Jisu Kim, Su-Young Han, Hyeyoung MinAbstractThe sense of vision is the primary means by which we gather information from our surroundings, and vision loss, therefore, severely compromises the life of the affected individuals, their families, and society. Loss of vision becomes more frequent with age, and diabetic retinopathy, age-related macular degeneration, cataracts, and glaucoma are the major causes of vision impairment. To find active pharmacological compounds that might prevent or ameliorate the vision-threatening eye dis...
Source: Journal of Ginseng Research - Category: Complementary Medicine Source Type: research
Conclusions: NAFLD severity was associated with high IOP (>15 mm Hg) in Korean adults in a dose-dependent manner.
Source: Journal of Glaucoma - Category: Opthalmology Tags: Original Studies Source Type: research
Implantable technologies have come a long way over the years, and advancements in micro and nanotechnologies have helped device developers continue to push the envelope even further. Within the realm of drug delivery, advances in nanotechnologies have consistently improved patient outcomes by enabling sustained drug delivery to help treat chronic conditions. These scalable technologies have even offered localized drug delivery that can further improve bioavailability. While many of these technologies offer a variety of opportunities, we’re still eagerly awaiting to see the impact of these advancements onc...
Source: MDDI - Category: Medical Devices Authors: Tags: BIOMEDevice San Jose Implants Source Type: news
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