Is Obesity Associated With Increased Risk of Deep Vein Thrombosis or Pulmonary Embolism After Hip and Knee Arthroplasty? A Large Database Study.

CONCLUSIONS: This large administrative database study suggests that patient classification as overweight or obese is associated with increased risk of development of PE but not DVT after primary THA or TKA. Because aggressive pharmacologic anticoagulation regimens can decrease the DVT rate but have not been shown to affect the rate of PE or death, the data do not currently support increased anticoagulation in patients with obesity without other risk factors for VTE undergoing THA or TKA. Additional studies are required to refine VTE prophylaxis protocols to reduce PE risk while maintaining acceptable postoperative bleeding risk. LEVEL OF EVIDENCE: Level III, therapeutic study. PMID: 30624321 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30624321?dopt=Abstract

Source: Clinical Orthopaedics and Related Research - January 3, 2019 Category: Orthopaedics Authors: Sloan M, Sheth N, Lee GC Tags: Clin Orthop Relat Res Source Type: research