Toxicological profile of Amanita virosa - a narrative review

Publication date: Available online 9 January 2019Source: Toxicology ReportsAuthor(s): Milad Tavassoli, Asma Afshari, Andree Letiţia Arsene, Bruno Mégarbane, Josef Dumanov, Monica Maria Bastos Paoliello, Aristidis Tsatsakis, Félix Carvalho, Mahmoud Hashemzaei, Ramin RezaeeAbstractMushrooms account for a part of human diet due to their exquisite taste and protein content as well as their promising health effects unveiled by scientific research. Toxic and non-toxic mushrooms frequently share considerable morphological similarities, which mislead the collectors/consumers, resulting in mycotoxicity. Numerous mushroom species are considered “poisonous” as they produce dangerous toxins. For instance, members of the genus Amanita, especially A. phalloides, A. virosa and A. verna, are responsible for severe and even life-threatening noxious consequences. Globally, mushroom poisoning is a crucial healthcare issue as it leads to a considerable number of deaths annually. However, no definite antidote has been introduced to treat this poisoning. The present article discusses the characteristics of A. virosa in terms of epidemiology, mechanisms of toxicity, poisoning features and management.Graphical abstract
Source: Toxicology Reports - Category: Toxicology Source Type: research

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Authors: Caparros Lefebvre D Abstract In the 90's, clinico pathological studies have considerably improved the diagnosis of specific and rare neurodegenerative diseases. After a training in Parkinsons' disease in Paris, the author moved to French West Indies (Guadeloupe) and observed a high incidence of atypical parkinsonism with dementia, unresponsive to levodopa. Similar features were observed in Martinique. An environmental origin has been suspected with the exposure to toxins of annonaceae leaves and seeds. The candidate toxins are acetogenins acting as mitochondrial poison. This was demonstrated in neuronal ce...
Source: Revue Neurologique - Category: Neurology Tags: Rev Neurol (Paris) Source Type: research
Introduction: Poisoning exposure cases involving e-cigarettes have increased since 2010, coinciding with increasing rates of e-cigarette use in the United States (US). Given the increasing prevalence of e-cigarette use and ever-changing product desi...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news
William Withering the British Botanist of 18th century now laid to rest in the St Barthomlew Churchyard ,Edgbaston is known for his astonishing isolation of the wonder moelcule Digoxin from Foxglove. (Of course, let us not forget original old lady Ms. Hutton from Shropshire who was treating epidemic dropsy with a concoction of herbal Tea ) He reported this in the seminal paper “An account of Foxglove’ in the year 1750 and subsequently became a fellow of Royal college of science. (The story of Withering and Digoxin is extensively researched and written by Dr Dennis M, Krikler in a classic review article of 198...
Source: Dr.S.Venkatesan MD - Category: Cardiology Authors: Tags: cardiac failure history of cardiology dig trial radiance proved history of digoxin Source Type: blogs
Abstract Aluminum phosphide (AlP) is considered now one of the most common causes of poisoning among agricultural pesticides. Poisoning with AlP is extremely toxic to humans with high mortality rate. The aim of this work was to evaluate the prognostic factors and outcome of acute aluminum phosphide poisoning in Alexandria Main University Hospital during a period of 6 months from 1 November 2017 until the end of April 2018, highlighting the role of SOFA score and echocardiography in predicting the mortality. The prospective study was conducted on all patients admitted with acute AlP poisoning to Alexandria Main Uni...
Source: Environmental Science and Pollution Research International - Category: Environmental Health Authors: Tags: Environ Sci Pollut Res Int Source Type: research
I’ll get right to the dismal data: Americans are dying from poison at an alarming rate. In 2005, death by poison in the U.S. occurred in about 11 of every 100,000 people over age 15. By 2016, that number had … Continue reading → The post Death by Poison – A New American Epidemic appeared first on PeterUbel.com.
Source: blog.bioethics.net - Category: Medical Ethics Authors: Tags: Health Care Peter Ubel syndicated Uncategorized Source Type: blogs
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Source: Molecular Phylogenetics and Evolution - Category: Molecular Biology Source Type: research
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Source: Chemical Engineering Journal - Category: Chemistry Source Type: research
This study aimed to challenge the traditional separation into "violent" and "non-violent" suicides by generating a cluster analysis with a data-driven, machine learning approach. In a retrospective analysis, data on all officially confirmed suicides (N = 77,894) in Austria between 1970 and 2016 were assessed. Based on a defined distance metric between distributions of suicides over age group and month of the year, a standard hierarchical clustering method was performed with the five most frequent suicide methods. In cluster analysis, poisoning emerged as distinct from all other methods - both in the...
Source: Journal of the Association of European Psychiatrists - Category: Psychiatry Tags: Eur Psychiatry Source Type: research
Abstract Fe/activated coke (AC) and Cr-Fe/AC catalysts with AC as a supporter and Cr and Fe as active components were prepared by an impregnation method for low-temperature selective catalytic reduction (SCR) of NO with NH3. The effects of Cr addition and its concentrations on the deNOx performance of Fe/AC catalysts were studied at low temperature. The Cr addition promotes the low-temperature SCR activity of the 8Fe/AC catalyst and the 8Fe6Cr/AC catalyst has the best low-temperature SCR deNOx performance, which the NOx conversions are greater than 90% at 160-240 °C. The 8Fe6Cr/AC catalyst has good water resis...
Source: Environmental Science and Pollution Research International - Category: Environmental Health Authors: Tags: Environ Sci Pollut Res Int Source Type: research
ngfeng Li Around 90% of all fatal and non-fatal unintentional injuries occur in low- and middle-income countries (LMICs). The magnitude of unintentional injuries is unclear due to limited research and data. This paper describes the burden of lesser-known injuries (LKIs—cut injuries, unintentional poisoning, machine injuries, electrocution, injury by blunt objects, and suffocation) in rural Bangladesh, using data from the Saving of Lives from Drowning (SoLiD) project in Bangladesh. Descriptive statistics were used to report counts and rates of injuries by socio-demographic factors, injury characteristics, and ...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
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