[Genetics of Amyotrophic Lateral Sclerosis].

[Genetics of Amyotrophic Lateral Sclerosis]. Praxis (Bern 1994). 2019 Jan;108(1):37-44 Authors: Czell D Abstract Genetics of Amyotrophic Lateral Sclerosis Abstract. In recent years, the knowledge of gene mutation that can lead to amyotrophic lateral sclerosis (ALS), frontotemporal dementia, or a FTD-ALS complex has been drastically improvedwith the help of next-generation sequencing (NGS), so that many new genes and their molecular genetic mechanisms and symptoms of the patients could be described. For example it was found that in the same family with the same gene mutation patients with ALS, FTD or another neurodegenerative disease can be found. The knowledge about the genes does not only contribute to the understanding of these diseases, but should help develop new therapeutic possibilities. PMID: 30621546 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/30621546?dopt=Abstract

Source: Praxis - January 1, 2019 Category: General Medicine Authors: Czell D Tags: Praxis (Bern 1994) Source Type: research