Technical Feasibility and Design of a Shape Memory Alloy Support Device to Increase Ejection Fraction in Patients with Heart Failure

ConclusionsThis study demonstrated the feasibility of volume displacement in a static heart model by activation of SMA-wires. Configuration, duty cycle, frequency, pulse intervals and diameter were identified as important factors affecting the activation of SMA-wires on volume displacement. Future research should include the use of parallel SMA-wires, prototype testing in dynamic orex vivo bench models.
Source: Cardiovascular Engineering and Technology - Category: Cardiology Source Type: research

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Cardiac resynchronization therapy (CRT) is a standard treatment for selected patients with chronic heart failure (HF). However, up to 30-50% of patients still do not respond to CRT.
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research
Cardiac resynchronization therapy (CRT) via bi-ventricular pacing has demonstrated clinical benefits in heart failure (HF) patients with ventricular dyssynchrony. Other approaches of CRT is little known.
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research
This study investigated the association between ICD use and all-cause mortality in a contemporary reduced ejection fraction (HFrEF) cohort with a focus on subgroups. The study population was compiled from patients in the Swedish Heart Failure Registry (SwedeHF) fulfilling ESC criteria for primary prevention ICD use. Propensity score matching was used to account for differences at baseline. In a release principal investigator Dr. Benedikt Schrage of the Karolinska Institute in Stockholm, Sweden said: “Most randomized trials on ICD use for primary prevention of sudden cardiac death in HFrEF enrolled patient...
Source: MDDI - Category: Medical Devices Authors: Tags: Cardiovascular Source Type: news
varese G Abstract BACKGROUND: Most randomized trials on implantable cardioverter-defibrillator (ICD) use for primary prevention of sudden cardiac death in heart failure with reduced ejection fraction (HFrEF) enrolled patients>20 years ago. We investigated the association between ICD use and all-cause mortality in a contemporary HFrEF cohort and examined relevant subgroups. METHODS: Patients from the Swedish HF Registry (SwedeHF) fulfilling the European Society of Cardiology criteria for primary prevention ICD were included. The association between ICD use and 1-year and 5-year all-cause and cardiovascular ...
Source: Circulation - Category: Cardiology Authors: Tags: Circulation Source Type: research
– The beneficial effects of a cardiac resynchronization defibrillator (CRT-D) in patients with heart failure, low LVEF, and wide QRS have clearly been established. Nevertheless, mortality remains high in some patients. The aim of this study was to develop and validate a risk score to identify pati ents at high risk for early mortality who are implanted with a CRT-D.
Source: Journal of Cardiac Failure - Category: Cardiology Authors: Source Type: research
CONCLUSIONS: The population of CRT recipients in Poland and other European countries did not differ in terms of demographic and clinical characteristics. In most cases, indications for CRT were in accordance with the guidelines; however some devices were implanted in patients beyond the guideline recommendations. For these procedures, the decision regarding CRT im-plantation relies mainly on the physicians' experience. PMID: 30406939 [PubMed - indexed for MEDLINE]
Source: Kardiologia Polska - Category: Cardiology Authors: Tags: Kardiol Pol Source Type: research
SUNNYVALE, Calif., Aug. 27, 2019 -- (Healthcare Sales &Marketing Network) -- EBR Systems, Inc., developer of the world's only wireless cardiac pacing system for heart failure, today announced it has closed $30M in new funding to complete enrollment of it... Devices, Cardiology, Venture Capital, Personnel EBR Systems, cardiac pacing, Cardiac Resynchronization Therapy, WISE CRT
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news
CVRx, a Minneapolis, Minnesota company, won FDA approval for the first neuromodulation device designed to address heart failure. Intended as a treatment option for patients with an ejection fraction ≤35% and New York Heart Failure Classification o...
Source: Medgadget - Category: Medical Devices Authors: Tags: Cardiac Surgery Cardiology Vascular Surgery Source Type: blogs
AbstractTo determine (a) whether chronic heart failure with reduced ejection fraction (HFrEF) is associated with increased glycocalyx shedding; (b) whether glycocalyx shedding in HFrEF with left ventricular dyssynchrony is related to inflammation, endothelial dysfunction and/or redox stress and is ameliorated by cardiac resynchronisation therapy. Glycocalyx shedding has been reported to be increased in heart failure and is a marker of increased mortality. Its role in dyssynchronous systolic heart failure and the effects of cardiac resynchronisation therapy (CRT) are largely unknown. Twenty-six patients with dyssynchronous ...
Source: Heart and Vessels - Category: Cardiology Source Type: research
ConclusionsSARM predicts non ‐response to CRT and may help in the selection of CRT candidates.This article is protected by copyright. All rights reserved
Source: Pacing and Clinical Electrophysiology : PACE - Category: Cardiology Authors: Tags: DEVICES Source Type: research
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