A comparative analysis of overall survival between high-dose-rate and low-dose-rate brachytherapy boosts for unfavorable-risk prostate cancer

External beam radiation therapy (EBRT) with low-dose-rate (LDR) brachytherapy boost has been associated with improved biochemical progression –free survival and overall survival (OS) compared with dose-escalated EBRT (DE-EBRT) alone for unfavorable-risk prostate cancer. However, it is not known whether high-dose-rate (HDR) boost provides a similar benefit. We compare HDR boost against LDR boost and DE-EBRT with respect to OS.

Source: Brachytherapy - January 9, 2019 Category: Cancer & Oncology Authors: Martin T. King, David D. Yang, Vinayak Muralidhar, Brandon Mahal, Santino Butler, Phillip M. Devlin, Larissa J. Lee, Kent. W. Mouw, Neil M. Martin, Anthony V. D'Amico, Paul L. Nguyen, Peter F. Orio Source Type: research