Endovascular Treatment of Cerebral Venous Sinus Thrombosis and Insights into Intracranial Coagulopathy

We describe a medically-refractory case of CVST in a 35-year-old woman later found to have JAK2 mutation and essential thrombocytosis. Despite therapeutic anticoagulation levels, worsening cerebral edema and progression to coma prompted endovascular treatment. Failed endovascular thrombectomy attempts led to placement of 2 separate indwelling microcatheters for continuous infusion of tissue plasminogen activator (tPA).

Source: Journal of Stroke and Cerebrovascular Diseases - January 9, 2019 Category: Neurology Authors: David Roh, Jason Carroll, Kara Melmed, Mitchell S.V. Elkind, Andrew Eisenberger, Richard Francis, Soojin Park, Sachin Agarwal, Jan Claassen, Philip M. Meyers Tags: Case Report Source Type: research