Effects of Atypical Antipsychotic Treatment and Resistant Starch Supplementation on Gut Microbiome Composition in a Cohort of Patients with Bipolar Disorder or Schizophrenia

ConclusionThese data suggest that AAP treatment is associated with measurable differences in gut microbiota, particularly in female AAP ‐treated patients in whom reduced species richness was observed. Additionally, variable microbiome responses to resistant starch supplementation were seen, with a significant increase in starch degraders.This article is protected by copyright. All rights reserved.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - Category: Drugs & Pharmacology Authors: Tags: Original Research Article Source Type: research

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Source: Journal of Psychiatric Practice - Category: Psychiatry Tags: Clinical Case Discussions Source Type: research
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Source: CNS Neuroscience and Therapeutics - Category: Neuroscience Authors: Tags: CNS Neurosci Ther Source Type: research
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Source: Molecular Metabolism - Category: Endocrinology Source Type: research
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Previous studies have identified shifts in gut microbiota associated with AAP-treatment, which may link AAPs to metabolic burden. Dietary prebiotics, like resistant starch (RS) may be beneficial in obesity and glucose regulation, but little is known mechanistically about its ability to modify gut microbiota in AAP-treated individuals. This investigation was undertaken to mechanistically delineate the effects of AAP-treatment and RS on gut microbiota in a psychiatric population.
Source: Biological Psychiatry - Category: Psychiatry Authors: Source Type: research
Conditions:   Obesity;   Ketogenic Dieting;   Metabolic Syndrome;   Bipolar Disorder;   Schizophrenia;   Weight Gain;   Psychotropic Drug, Unspecified Causing Adverse Effects in Therapeutic Use Intervention:   Other: LCHF, Ketogenic Diet Sponsors:   Stanford University;   Obesity Treatment Foundation Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
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