Impact of angiogenic activation and inhibition on miRNA profiles of human retinal endothelial cells.

CONCLUSION: In this study we characterized the miRNA profile of HRMVECs under resting, angiogenic and anti-angiogenic conditions and identified several miRNAs of potential pathophysiologic importance for angioproliferative retinal diseases. Our results have implications for possible miRNA-targeted angiomodulatory approaches in diseases like diabetic retinopathy or retinopathy of prematurity.
PMID: 30615884 [PubMed - as supplied by publisher]

Source: Experimental Eye Research - January 4, 2019 Category: Opthalmology Authors: Walz JM, Wecker T, Zhang PP, Cakir B, Gruening B, Agostini H, Reuer T, Ludwig F, Boneva S, Faerber L, Lange C, Schlunck GR, Stahl A Tags: Exp Eye Res Source Type: research