New Method Could Lead to Materials to Promote Natural Healing

A team of researchers from the Imperial College in London have created a new process known as traction force-activated payloads (TrAPs) that could have an impact on the body’s ability to heal. The method, developed by Dr. Ben Almquist and a team at Imperial College London, allows materials to speak to the body’s natural repair systems to drive healing. In the TrAPs process, researchers folded DNA segments into 3-D shapes known as aptamers that cling tightly to proteins. Then, the researchers attached a customizable ‘handle’ that cells can grab onto on one end, before attaching the opposite end to a scaffold such as collagen. Are you ready for MD&M West? Join us from Feb. 5 - Feb. 7 for medtech's premiere event in Anaheim, CA.   The researchers said they also found that by changing the cellular 'handle', they can change which type of cell can grab hold and pull, letting them tailor TrAPs to release specific therapeutic proteins based on which cells are present at a given point in time. In doing so, the TrAPs produce materials that can smartly interact with the correct type of cell at the correct time during wound repair. "The TrAPs technology provides a flexible method to create materials that actively communicate with the wound and provide key instructions when and where they are needed,” Almquist said in a release. “This sort of ...
Source: MDDI - Category: Medical Devices Authors: Tags: Materials Source Type: news