Vitamin D in burn-injured patients

Publication date: February 2019Source: Burns, Volume 45, Issue 1Author(s): Megan A. Rech, Daniel Colon Hidalgo, Jennifer Larson, Sarah Zavala, Michael MosierAbstractRecently, many studies have demonstrated pleotropic effects of vitamin D, including immune modulation and cardiovascular system activity. Sufficient vitamin D concentrations and supplementation of vitamin D may be of benefit in burn-injured patients. Low 25(OH)D has been observed in nearly all pediatric and most adult burn patients. Vitamin D has primarily been studied in pediatric burn patients, focusing on bone marker measurements and the incidence of fractures. The preferred vitamin D dose, formulation, and route of administration remain unknown, and there is limited data on the impact of vitamin D status on clinical outcomes. Further research should focus on determining optimal monitoring strategies, supplementation regimens and clinical outcomes like mortality, length of stay and incidence of sepsis.
Source: Burns - Category: Dermatology Source Type: research