Target sequencing of cancer-related genes in early esophageal squamous neoplasia resected by endoscopic resection in Japanese patients.

Conclusions: Mutations of TP53 and CDKN2A, and PIK3CA amplification were common in early esophageal squamous neoplasia, while other mutations accumulated with disease progression. An understanding of these molecular events might provide a molecular basis for early lesion treatment. PMID: 30613367 [PubMed]

https://www.ncbi.nlm.nih.gov/pubmed/30613367?dopt=Abstract

Source: Oncotarget - January 8, 2019 Category: Cancer & Oncology Tags: Oncotarget Source Type: research