Response to letter to the editor by Dr. Kobayashi and colleagues

We appreciate the clarification provided by Kobayashi and colleagues. Using the modified Duarte formula1 does not provide an absolute plasma volume assessment but rather an estimate and unlike the Kaplan-Hakim formula, the Duarte formula has the unit of dL/g. While the commonly used PV formulas do not accurately reflect the measured PV, a distinction of our analysis was to point out that while such estimates cannot be used to guide volume management therapy in the individual patient, there remains a prognostic value of the formula estimates2 –4 correlating with short and mid-term clinical outcomes in patients with heart failure.
Source: Journal of Cardiac Failure - Category: Cardiology Authors: Tags: Letter to the Editor Source Type: research