UNC119 promoted cell growth and migration by Wnt/ β-catenin signal and TGF-β/EMT signal pathway in hepatocellular carcinoma.

CONCLUSION: UNC119 is significantly up-regulated and promoted cell growth and migration in hepatic cancer cells and tissues via Wnt/β-catenin signal pathway and TGF-β/EMT signal pathway, respectively. Anti-UNC119 treatment inhibited cell proliferation, growth, migration and invasion through inhibition of Wnt/β-catenin and GF-β/EMT signal pathway, respectively. PMID: 30610799 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/30610799?dopt=Abstract

Source: Journal of B.U.ON. - January 7, 2019 Category: Cancer & Oncology Tags: J BUON Source Type: research